Drug comparisons
Alogliptin vs Glyburide
Alogliptin vs Glyburide: Alogliptin (DPP-4) has low hypo and weight gain risks but heart failure warning. Glyburide (sulfonylurea) risks weight gain and hypo.
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Clinical context
Patients with type 2 diabetes not responding well to metformin may be prescribed alogliptin or glyburide as add-on therapy.
Bottom line
Both Alogliptin and Glyburide can be effective for type 2 diabetes but the better option for you depends on your personal health profile and risk factors.
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