Drug comparisons
Angiotensin II vs Norepinephrine
Compare Angiotensin II (Giapreza) and Norepinephrine (Levophed) as vasopressors for shock. Differences in mechanism of action and clinical scenarios where one may be preferred.
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Clinical context
This comparison is triggered when selecting add-on vasopressors for vasodilatory shock unresponsive to fluids and initial catecholamines.
Bottom line
Norepinephrine is preferred first-line with angiotensin II as a useful adjunct in refractory cases.
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