Drug comparisons
Canagliflozin vs Glimepiride
Canagliflozin vs glimepiride: SGLT2 inhibitor vs sulfonylurea. Canagliflozin lowers blood sugar by kidney glucose prevention; glimepiride by insulin boost.
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Clinical context
Patients with type 2 diabetes not controlled by metformin may compare canagliflozin and glimepiride as add-on therapies.
Bottom line
Both canagliflozin and glimepiride are effective oral treatments for type 2 diabetes, but selection should be based on patient-specific factors.
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