Drug comparisons
Dapagliflozin vs Glimepiride
Compare Dapagliflozin (Farxiga) vs Glimepiride (Amaryl) for type 2 diabetes: SGLT2 vs sulfonylurea differences in heart/kidney benefits, hypo risk, weight, and cost.
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Clinical context
Triggered when adding second-line therapy after metformin or switching due to cardiovascular disease, hypoglycemia, or cost in type 2 diabetes.
Bottom line
Dapagliflozin is generally preferred for most patients due to proven heart and kidney benefits plus safer hypoglycemia profile, though Glimepiride suits cost-limited cases without those risks.
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