Drug comparisons
Nitroglycerin vs Propafenone
Nitroglycerin vs propafenone: A nitrate vasodilator treating angina and heart failure compared to a class Ic antiarrhythmic for atrial fibrillation with a black box warning.
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Clinical context
This comparison occurs in patients with coronary disease who also develop atrial fibrillation needing both anti-ischemic and rhythm-control therapy.
Bottom line
Nitroglycerin and propafenone address completely different cardiac mechanisms and cannot substitute for each other.
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