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Serum Albumin

Published: July 27, 2026Updated: August 25, 2026

Serum albumin measures the concentration of albumin, a protein produced by the liver, in the blood. It helps assess liver function and nutritional status.

Quick summary

Serum albumin is a key indicator of liver function and nutritional status.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

Units
g/dL
Clinical utility
diagnostic
Result kind
quantitative
FDA-cleared
Roche Albumin, Abbott Albumin, Siemens Albumin
interpretation: {"text":"May indicate liver dysfunction, malnutrition, or inflammation.","label":"Low"}; {"text":"Typically due to dehydration or excessive protein intake.","label":"High"}

Serum albumin is a protein synthesized by the liver and is the most abundant protein in blood plasma. It plays a crucial role in maintaining oncotic pressure, transporting hormones, vitamins, and drugs, and providing amino acids when needed.

A low serum albumin level (hypoalbuminemia) can indicate liver disease, such as cirrhosis or hepatitis, as the liver's ability to synthesize albumin is compromised. It can also suggest malnutrition, inflammation, or kidney disease.

Conversely, high albumin levels (hyperalbuminemia) are less common and may be due to dehydration or high protein intake. However, this is not typically a cause for concern unless other symptoms are present.

Frequently asked questions

What does a low serum albumin level mean?
A low serum albumin level can indicate liver disease, malnutrition, or inflammation.
What is the normal range for serum albumin?
The normal range for serum albumin is typically between 3.5 and 5.0 g/dL.
  1. 1
    Mayo Clinic: Albumin testSource
  2. 2
    MedlinePlus: Albumin Blood TestSource

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy