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Anti-GBM Antibody

Published: July 27, 2026Updated: August 25, 2026

The Anti-GBM Antibody test measures the level of antibodies targeting the glomerular basement membrane, which can indicate autoimmune kidney disease.

Quick summary

Anti-GBM Antibody titer helps diagnose autoimmune kidney conditions.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

Units
titer
Clinical utility
diagnostic
Result kind
qualitative
FDA-cleared
Roche Anti-GBM, Abbott Anti-GBM, Euroimmun Anti-GBM
interpretation: {"text":"0–1 titer: No significant level of Anti-GBM antibodies detected.","label":"Normal"}; {"text":">1 titer: Presence of Anti-GBM antibodies, indicative of potential autoimmune kidney disease.","label":"Elevated"}

The Anti-GBM Antibody test is a diagnostic tool used to detect the presence of anti-glomerular basement membrane antibodies in the blood. These antibodies attack the kidneys and can cause severe damage if left untreated.

This biomarker is particularly important in diagnosing Goodpasture's syndrome, a rare but serious autoimmune condition that affects both the kidneys and the lungs. Elevated levels of Anti-GBM antibodies are a strong indicator of this disease.

A titer of 0–1 is considered normal, while higher titers suggest the presence of anti-GBM antibodies and warrant further investigation. Early detection and treatment are crucial for preventing irreversible kidney damage.

Frequently asked questions

What is the normal range for Anti-GBM Antibody levels?
A titer of 0–1 is considered normal.
What does a high Anti-GBM Antibody titer indicate?
A high titer indicates the presence of Anti-GBM antibodies, suggesting autoimmune kidney disease such as Goodpasture's syndrome.
  1. 1
    Goodpasture's Syndrome - National Kidney FoundationSource
  2. 2
    Anti-GBM Antibodies - MedlinePlusSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy