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Anti-MCV (Antibodies against Modified Citrullinated Vimentin)

Published: July 27, 2026Updated: August 25, 2026

Anti-MCV measures antibodies in the blood targeting citrullinated vimentin, a protein that is modified in inflammatory conditions like rheumatoid arthritis.

Quick summary

Anti-MCV is a diagnostic biomarker for inflammatory conditions, particularly rheumatoid arthritis.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

Units
U/mL
Clinical utility
diagnostic
Result kind
quantitative
FDA-cleared
Roche Anti-MCV, Thermo Anti-MCV
interpretation: {"text":"Levels above 20 U/mL may indicate an inflammatory condition such as rheumatoid arthritis.","label":"Elevated"}; {"text":"Levels within the range of 0–20 U/mL are typically considered normal.","label":"Normal"}

Anti-MCV (Antibodies against Modified Citrullinated Vimentin) is a blood test that detects antibodies targeting citrullinated vimentin, a protein that undergoes changes in inflammatory conditions such as rheumatoid arthritis.

The presence of these antibodies can indicate an autoimmune response, making Anti-MCV a valuable tool for diagnosing and monitoring inflammatory diseases.

Levels of Anti-MCV above the reference range (0–20 U/mL) may suggest an increased risk or presence of inflammatory conditions, particularly rheumatoid arthritis.

Frequently asked questions

What is the normal range for Anti-MCV?
The normal range for Anti-MCV is 0–20 U/mL.
What does a high Anti-MCV level mean?
A high Anti-MCV level may indicate an inflammatory condition, particularly rheumatoid arthritis.
  1. 1
    Anti-MCV: A Promising Biomarker for Rheumatoid ArthritisSource
  2. 2
    Role of Anti-MCV in Rheumatoid Arthritis DiagnosisSource

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy