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Apolipoprotein B

Published: July 27, 2026Updated: August 25, 2026

Apolipoprotein B (ApoB) is a protein component of low-density lipoprotein (LDL) particles, which are often referred to as 'bad cholesterol.' It measures the total number of atherogenic particles in the blood.

Quick summary

ApoB is a key marker for assessing cardiovascular risk by measuring the number of 'bad cholesterol' particles.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

Units
mg/dL
Clinical utility
screening
Result kind
quantitative
FDA-cleared
Roche ApoB, Abbott ApoB, Siemens ApoB
interpretation: {"text":"ApoB levels between 0–60 mg/dL are generally considered low risk for cardiovascular disease.","label":"Low Risk"}; {"text":"ApoB levels above 100 mg/dL may indicate a higher risk of cardiovascular disease and warrant further evaluation.","label":"High Risk"}

Apolipoprotein B (ApoB) is a crucial protein found in low-density lipoprotein (LDL) particles, commonly known as 'bad cholesterol.' Measuring ApoB levels provides insight into the total number of atherogenic particles circulating in the bloodstream.

Elevated ApoB levels are associated with an increased risk of cardiovascular diseases, including heart attacks and strokes. This is because ApoB reflects the concentration of LDL particles, which can contribute to arterial plaque formation.

For optimal cardiovascular health, ApoB levels should be kept within a specific range. Screening for ApoB can help identify individuals at risk and guide preventive interventions, such as lifestyle changes or medication.

Frequently asked questions

What is the normal range for Apolipoprotein B?
The reference range for ApoB is typically between 0–100 mg/dL, with levels below 60 mg/dL considered optimal for most individuals.
How can I lower my ApoB levels?
Lifestyle changes such as a healthy diet, regular exercise, and medication (if prescribed) can help lower ApoB levels and reduce cardiovascular risk.
  1. 1
    National Lipid Association Recommendations for Patient-Centered Management of DyslipidemiaSource
  2. 2
    American Heart Association: Apolipoprotein BSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy