Skip to content

Bentiromide (PABA) Test

Published: July 27, 2026Updated: August 25, 2026

The Bentiromide (PABA) test measures the ability of the pancreas to digest proteins by assessing the breakdown of bentiromide into para-aminobenzoic acid (PABA).

Quick summary

The Bentiromide (PABA) test assesses pancreatic exocrine function.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

Units
%
Clinical utility
diagnostic
Result kind
quantitative
FDA-cleared
FDA Cleared Pancreatic Assay
interpretation: {"text":"80–100% PABA recovery indicates normal pancreatic exocrine function.","label":"Normal"}; {"text":"Less than 80% PABA recovery may indicate pancreatic insufficiency or other pancreatic disorders.","label":"Abnormal"}

The Bentiromide (PABA) test is a diagnostic tool used to evaluate the exocrine function of the pancreas. It involves administering bentiromide, a synthetic peptide, and measuring the amount of PABA excreted in the urine.

A healthy pancreas will digest bentiromide and release PABA, which is then absorbed by the body and excreted in the urine. The test measures the percentage of PABA recovered in the urine.

A result within the reference range of 80–100% indicates normal pancreatic function. Lower percentages may suggest exocrine pancreatic insufficiency or other pancreatic disorders.

Frequently asked questions

What is the purpose of the Bentiromide (PABA) test?
The test assesses the exocrine function of the pancreas by measuring the digestion and absorption of bentiromide.
What does a low PABA recovery percentage mean?
A low percentage may indicate that the pancreas is not producing enough digestive enzymes, suggesting pancreatic insufficiency.
  1. 1
    Bentiromide TestSource
  2. 2
    Pancreatic Function TestsSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy