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High-Sensitivity C-Reactive Protein (hs-CRP)

Published: July 27, 2026Updated: August 25, 2026

High-sensitivity C-Reactive Protein (hs-CRP) is a biomarker that measures low levels of inflammation in the body, which is associated with cardiovascular risk.

Quick summary

hs-CRP is used to assess cardiovascular risk by measuring inflammation.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

Units
mg/L
Clinical utility
screening
Result kind
quantitative
FDA-cleared
Roche hs-CRP, Abbott hs-CRP, Siemens hs-CRP
interpretation: {"text":"hs-CRP levels ≤ 1 mg/L indicate a lower risk of cardiovascular disease.","label":"Low Risk"}; {"text":"hs-CRP levels > 1 mg/L may suggest an increased risk of cardiovascular events.","label":"High Risk"}

High-sensitivity C-Reactive Protein (hs-CRP) is a protein produced by the liver in response to inflammation. It is a sensitive marker that can detect low-grade inflammation, which is often linked to an increased risk of cardiovascular diseases.

The normal reference range for hs-CRP in cardiovascular risk assessment is 0–1 mg/L. Levels above this range may indicate a higher risk of heart disease, even in the absence of symptoms.

hs-CRP is particularly useful in screening individuals with intermediate cardiovascular risk, helping clinicians to refine risk stratification and guide preventive interventions.

Frequently asked questions

What is the normal range for hs-CRP?
The normal range for hs-CRP in cardiovascular risk assessment is 0–1 mg/L.
How can I lower my hs-CRP levels?
Lifestyle changes such as regular exercise, a healthy diet, and smoking cessation can help lower hs-CRP levels.
  1. 1
    C-Reactive Protein (CRP) as a Biomarker for Cardiovascular DiseaseSource
  2. 2
    High-sensitivity C-reactive protein (hs-CRP)Source

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy