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Fecal Elastase-1

Published: July 27, 2026Updated: August 25, 2026

Fecal Elastase-1 measures the concentration of elastase, an enzyme produced by the pancreas, in stool samples. It is used to assess pancreatic function and diagnose exocrine pancreatic insufficiency.

Quick summary

Fecal Elastase-1 is a diagnostic test for pancreatic function.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

Units
μg/g
Clinical utility
diagnostic
Result kind
quantitative
FDA-cleared
ScheBo Elastase-1, Bioserv Elastase-1
interpretation: {"text":"200–500 μg/g: Indicates normal pancreatic function.","label":"Normal"}; {"text":"< 200 μg/g: Suggests exocrine pancreatic insufficiency.","label":"Low"}

Fecal Elastase-1 is a biomarker that quantifies the levels of elastase, an enzyme secreted by the pancreas, in fecal matter. This measurement is crucial for evaluating the exocrine function of the pancreas, which is responsible for producing digestive enzymes.

The reference range for Fecal Elastase-1 is typically between 200–500 μg/g. Levels below 200 μg/g may indicate exocrine pancreatic insufficiency, a condition where the pancreas does not produce enough digestive enzymes, potentially leading to malabsorption and malnutrition.

This test is non-invasive and can be particularly useful in diagnosing chronic pancreatitis, cystic fibrosis, and other conditions affecting pancreatic function. It is also helpful in monitoring the effectiveness of enzyme replacement therapy in patients with pancreatic insufficiency.

Frequently asked questions

What is the purpose of the Fecal Elastase-1 test?
The test assesses pancreatic function and helps diagnose conditions like exocrine pancreatic insufficiency.
How is the Fecal Elastase-1 test performed?
It involves analyzing a stool sample for elastase levels, typically using an enzyme-linked immunosorbent assay (ELISA).
  1. 1
    Mayo Clinic: Pancreatic Function TestsSource
  2. 2
    National Institute of Diabetes and Digestive and Kidney Diseases: PancreatitisSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy