Skip to content

Fibrinogen

Published: July 27, 2026Updated: August 25, 2026

Fibrinogen is a protein produced by the liver that plays a crucial role in blood clotting. It is measured to assess the risk of cardiovascular diseases.

Quick summary

Fibrinogen is a key protein in blood clotting and a marker for cardiovascular risk.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

Units
mg/dL
Clinical utility
screening
Result kind
quantitative
FDA-cleared
Roche Fibrinogen, Siemens Fibrinogen, Stago Fibrinogen
interpretation: {"text":"Fibrinogen levels within the range of 200–393 mg/dL are considered normal.","label":"Normal"}; {"text":"Levels above 393 mg/dL may indicate an increased risk of cardiovascular events and warrant further investigation.","label":"Elevated"}

Fibrinogen is a glycoprotein synthesized by the liver and is essential for the final stage of the coagulation cascade, where it is converted into fibrin to form blood clots.

Elevated levels of fibrinogen in the blood are associated with an increased risk of atherosclerosis and thrombosis, making it a valuable biomarker for cardiovascular risk assessment.

Reference ranges for fibrinogen are typically between 200–393 mg/dL, and levels above this range may indicate a need for further cardiovascular evaluation.

Frequently asked questions

What does a high fibrinogen level mean?
A high fibrinogen level may indicate an increased risk of blood clots and cardiovascular diseases such as heart attack and stroke.
Can lifestyle changes affect fibrinogen levels?
Yes, lifestyle changes such as quitting smoking, regular exercise, and a healthy diet can help lower fibrinogen levels.
  1. 1
    Fibrinogen as a Biomarker for Cardiovascular DiseaseSource
  2. 2
    Role of Fibrinogen in Blood ClottingSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy