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Ghrelin

Published: July 27, 2026Updated: August 25, 2026

Ghrelin is a hormone primarily produced by the stomach that regulates hunger, food intake, and energy balance.

Quick summary

Ghrelin is a hunger hormone that helps regulate appetite and energy balance.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

Units
pg/mL
Clinical utility
diagnostic
Result kind
quantitative
FDA-cleared
FDA Cleared Metabolic Assay
interpretation: {"text":"May indicate conditions such as anorexia nervosa or hyperthyroidism, where appetite is suppressed.","label":"Low Levels"}; {"text":"May suggest conditions like Prader-Willi syndrome, obesity, or other disorders where appetite is increased.","label":"High Levels"}

Ghrelin, often referred to as the 'hunger hormone,' is a peptide hormone that is primarily produced by the stomach. It plays a crucial role in signaling the hypothalamus to stimulate appetite and food intake.

This biomarker is particularly important in understanding metabolic disorders, such as obesity and anorexia, as it influences energy homeostasis and body weight regulation.

Ghrelin levels typically rise before meals, promoting hunger, and decrease after eating. Abnormal levels can indicate issues with appetite regulation and metabolic function.

Frequently asked questions

What is the normal range for ghrelin levels?
The normal range for ghrelin levels is typically between 100–400 pg/mL.
How is ghrelin testing used in clinical practice?
Ghrelin testing is used to assess appetite disorders, metabolic conditions, and to monitor the effectiveness of weight management treatments.
  1. 1
    Ghrelin: Its Physiological Roles and Clinical ImplicationsSource
  2. 2
    Role of Ghrelin in Energy HomeostasisSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy