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Haptoglobin

Published: July 27, 2026Updated: August 25, 2026

Haptoglobin is a protein produced by the liver that binds to free hemoglobin in the blood, preventing its excretion and protecting the kidneys from damage.

Quick summary

Haptoglobin is a protein that binds to free hemoglobin in the blood.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

Units
g/L
Clinical utility
diagnostic
Result kind
quantitative
FDA-cleared
Roche Haptoglobin, Abbott Haptoglobin
interpretation: {"text":"May indicate hemolytic anemia or other conditions causing increased red blood cell destruction.","label":"Low"}; {"text":"Suggests inflammation, infection, or liver disease.","label":"High"}

Haptoglobin is primarily used as a diagnostic tool to detect and monitor hemolytic anemia, a condition characterized by the destruction of red blood cells.

The normal reference range for haptoglobin is typically between 0.3 and 2 g/L. Levels below this range may indicate increased red blood cell destruction.

Elevated haptoglobin levels can be seen in inflammatory conditions, infections, and certain liver diseases.

Frequently asked questions

What is the normal range for haptoglobin?
The normal reference range for haptoglobin is typically between 0.3 and 2 g/L.
What does a low haptoglobin level mean?
A low haptoglobin level may indicate hemolytic anemia or other conditions causing increased red blood cell destruction.
  1. 1
    Mayo Clinic: Haptoglobin TestSource
  2. 2
    Lab Tests Online: HaptoglobinSource

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy