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Glycated Hemoglobin (HbA1c) IFCC

Published: July 27, 2026Updated: August 25, 2026

HbA1c IFCC measures the percentage of hemoglobin that is glycated, reflecting average blood glucose levels over the past 2-3 months.

Quick summary

HbA1c IFCC is a key diagnostic marker for assessing long-term blood glucose control.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

Units
mmol/mol
Clinical utility
diagnostic
Result kind
quantitative
FDA-cleared
Roche HbA1c IFCC, Abbott HbA1c IFCC, NGSP Certified Analyzers
interpretation: {"text":"20–42 mmol/mol","label":"Normal"}; {"text":">42 mmol/mol indicates potential diabetes or poor glycemic control","label":"Elevated"}

Glycated Hemoglobin (HbA1c) IFCC is a standardized measure that quantifies the amount of hemoglobin bound to glucose in the blood. This biomarker is crucial for diagnosing and monitoring diabetes mellitus.

The IFCC reference measurement procedure ensures consistency and accuracy in HbA1c testing across different laboratories worldwide. It is expressed in mmol/mol units.

An HbA1c level between 20–42 mmol/mol is considered within the normal range, while higher values may indicate poor glycemic control and a higher risk of diabetes complications.

Frequently asked questions

How often should HbA1c be tested?
For individuals with diabetes, it is typically tested every 3-6 months to monitor glycemic control.
Can HbA1c be used for diagnosing diabetes?
Yes, HbA1c levels ≥48 mmol/mol are often used as a diagnostic criterion for diabetes.
  1. 1
    American Diabetes Association: Standards of Medical Care in DiabetesSource
  2. 2
    International Federation of Clinical Chemistry and Laboratory Medicine (IFCC)Source

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy