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Hepatitis B Virus Core IgG Antibody

Published: July 27, 2026Updated: August 25, 2026

This biomarker measures the level of IgG antibodies against the core antigen of the Hepatitis B virus, indicating current or past infection.

Quick summary

HBV Core IgG antibody test helps diagnose current or past Hepatitis B infection.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

Units
S/CO
Clinical utility
diagnostic
Result kind
qualitative
FDA-cleared
Roche Anti-HBc IgG, Abbott Anti-HBc IgG
interpretation: {"text":"S/CO ≤ 1: No current or past HBV infection detected.","label":"Negative"}; {"text":"S/CO > 1: Indicates current or past HBV infection.","label":"Positive"}

The Hepatitis B Virus (HBV) Core IgG Antibody test detects the presence of IgG antibodies produced by the immune system in response to the core antigen of the Hepatitis B virus.

A positive result (S/CO > 1) suggests exposure to HBV, either through past infection or chronic infection, while a negative result (S/CO ≤ 1) generally indicates no current or past infection.

This test is crucial for diagnosing HBV infection, assessing immunity, and guiding treatment strategies.

Frequently asked questions

What does a positive HBV Core IgG result mean?
A positive result suggests that you have been exposed to the Hepatitis B virus, either through past infection or chronic infection.
Can this test differentiate between current and past HBV infection?
No, this test alone cannot differentiate; additional tests like HBV surface antigen and HBV DNA are needed for a comprehensive diagnosis.
  1. 1
    CDC - Hepatitis B TestingSource
  2. 2
    WHO - Hepatitis B Fact SheetSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy