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Hemoglobin Electrophoresis

Published: July 27, 2026Updated: August 25, 2026

Hemoglobin electrophoresis measures the different types of hemoglobin in the blood to identify various hemoglobin disorders.

Quick summary

Hemoglobin electrophoresis identifies abnormal hemoglobin types to diagnose blood disorders.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

Units
pattern
Clinical utility
diagnostic
Result kind
qualitative
FDA-cleared
Bio-Rad Variant, Trinity CAPILLARYS
interpretation: {"text":"Presence of hemoglobin A (HbA) as the main type, with small amounts of hemoglobin A2 (HbA2) and hemoglobin F (HbF).","label":"Normal"}; {"text":"Detection of abnormal hemoglobin types such as hemoglobin S (HbS), hemoglobin C (HbC), or elevated HbF, indicating specific hemoglobinopathies.","label":"Abnormal"}

Hemoglobin electrophoresis is a laboratory test that separates the different types of hemoglobin present in a blood sample. This separation is based on the electrical charge of the hemoglobin molecules.

The test is primarily used to diagnose hemoglobinopathies, which are genetic disorders affecting hemoglobin structure or production. Examples include sickle cell anemia and thalassemia.

By analyzing the hemoglobin pattern, clinicians can identify abnormal hemoglobin types and determine the appropriate treatment or management strategies for patients.

Frequently asked questions

What is the purpose of hemoglobin electrophoresis?
The test is used to diagnose and confirm various hemoglobin disorders, including sickle cell anemia and thalassemia.
How is the sample collected for hemoglobin electrophoresis?
A blood sample is collected from a vein, usually in the arm, and sent to a laboratory for analysis.
  1. 1
    Mayo Clinic: Hemoglobin ElectrophoresisSource
  2. 2
    National Heart, Lung, and Blood Institute: HemoglobinopathiesSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy