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Interleukin-1 Beta

Published: July 27, 2026Updated: August 25, 2026

Interleukin-1 Beta (IL-1β) is a cytokine that plays a key role in inflammatory responses and is often elevated in acute and chronic inflammatory conditions.

Quick summary

IL-1β is a key inflammatory cytokine used to diagnose inflammatory conditions.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

Units
pg/mL
Clinical utility
diagnostic
Result kind
quantitative
FDA-cleared
FDA Cleared Inflammatory Assay
interpretation: {"text":"0–5 pg/mL: Levels within this range are considered normal and indicate no significant inflammation.","label":"Normal"}; {"text":">5 pg/mL: Levels above the reference range may indicate the presence of an inflammatory condition.","label":"Elevated"}

Interleukin-1 Beta (IL-1β) is a pro-inflammatory cytokine that is produced by activated macrophages and is involved in the initiation and amplification of inflammatory responses.

Elevated levels of IL-1β are commonly found in various inflammatory diseases, including rheumatoid arthritis, inflammatory bowel disease, and sepsis.

The measurement of IL-1β levels in the blood or other bodily fluids can aid in the diagnosis and monitoring of inflammatory conditions.

Frequently asked questions

What conditions can cause elevated IL-1β levels?
Elevated IL-1β levels can be caused by inflammatory conditions such as rheumatoid arthritis, inflammatory bowel disease, and sepsis.
How is IL-1β measured?
IL-1β is typically measured using immunoassays such as ELISA (Enzyme-Linked Immunosorbent Assay) in blood or other bodily fluids.
  1. 1
    Interleukin-1 BetaSource
  2. 2
    Role of IL-1 in InflammationSource

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy