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Low-Density Lipoprotein Cholesterol (LDL-C)

Published: July 27, 2026Updated: August 25, 2026

LDL-C measures the amount of 'bad' cholesterol in the blood, which can contribute to the formation of plaques in arteries, leading to cardiovascular diseases.

Quick summary

LDL-C is a key indicator of cardiovascular risk due to its role in arterial plaque formation.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

Units
mg/dL
Clinical utility
screening
Result kind
quantitative
FDA-cleared
Roche LDL-C, Abbott LDL-C, Denka Seiken Direct LDL-C
interpretation: {"text":"0–100 mg/dL: Within the healthy range for most individuals.","label":"Normal"}; {"text":">100 mg/dL: Indicates an increased risk of cardiovascular disease; lifestyle changes or medication may be recommended.","label":"High"}

LDL-C, or low-density lipoprotein cholesterol, is often referred to as 'bad' cholesterol because high levels can lead to a buildup of cholesterol in the arteries.

This buildup can cause atherosclerosis, a condition where arteries become narrowed and hardened, increasing the risk of heart attack and stroke.

Screening for LDL-C is crucial for early detection and management of cardiovascular risk factors, especially in individuals with a family history of heart disease.

Frequently asked questions

What causes high LDL-C levels?
High LDL-C levels can be caused by a diet high in saturated and trans fats, lack of physical activity, smoking, and genetic factors.
How can I lower my LDL-C levels?
Lowering LDL-C levels can be achieved through a heart-healthy diet, regular exercise, quitting smoking, and, if necessary, medication such as statins.
  1. 1
    American Heart Association: LDL CholesterolSource
  2. 2
    Mayo Clinic: LDL Cholesterol TestSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy