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Matrix Metalloproteinase-7 (MMP-7)

Published: July 27, 2026Updated: August 25, 2026

MMP-7 is a biomarker that measures the levels of a specific enzyme involved in tissue remodeling and degradation of extracellular matrix proteins. It is particularly relevant in pulmonary diseases.

Quick summary

MMP-7 is a diagnostic biomarker for pulmonary conditions, measured in ng/mL with a reference range of 0–10 ng/mL.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

Units
ng/mL
Clinical utility
diagnostic
Result kind
quantitative
FDA-cleared
Roche MMP-7, R&D Systems MMP-7 ELISA
interpretation: {"text":"MMP-7 levels within the range of 0–10 ng/mL are considered normal.","label":"Normal"}; {"text":"Levels above 10 ng/mL may suggest the presence of a pulmonary disease such as IPF or COPD.","label":"Elevated"}

Matrix Metalloproteinase-7 (MMP-7), also known as matrilysin, is an enzyme that plays a crucial role in the degradation of extracellular matrix proteins. It is involved in various physiological processes, including tissue remodeling and wound healing.

In the context of pulmonology, elevated levels of MMP-7 have been associated with lung diseases such as idiopathic pulmonary fibrosis (IPF) and chronic obstructive pulmonary disease (COPD). The measurement of MMP-7 can aid in the diagnosis and monitoring of these conditions.

The normal reference range for MMP-7 is typically between 0–10 ng/mL. Levels above this range may indicate the presence of a pulmonary condition, necessitating further clinical evaluation.

Frequently asked questions

What is the role of MMP-7 in the body?
MMP-7 is involved in the degradation of extracellular matrix proteins and plays a role in tissue remodeling and wound healing.
How is MMP-7 measured?
MMP-7 levels are measured in ng/mL through a blood test, with a normal reference range of 0–10 ng/mL.
  1. 1
    Matrix Metalloproteinases in Lung DiseasesSource
  2. 2
    MMP-7 as a Biomarker for Pulmonary FibrosisSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy