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Myeloperoxidase Mass (MPO)

Published: July 27, 2026Updated: August 25, 2026

This biomarker measures the concentration of myeloperoxidase, an enzyme released by white blood cells, in the blood to assess cardiovascular inflammation and risk.

Quick summary

MPO mass assesses cardiovascular inflammation and risk.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

Units
ng/mL
Clinical utility
diagnostic
Result kind
quantitative
FDA-cleared
Abbott MPO, Roche MPO
interpretation: {"text":"MPO mass levels within the reference range (0–530 ng/mL) indicate a lower risk of cardiovascular events.","label":"Low Risk"}; {"text":"MPO mass levels above 530 ng/mL may suggest increased inflammation and a higher risk of cardiovascular disease.","label":"High Risk"}

Myeloperoxidase (MPO) is an enzyme found in white blood cells that plays a crucial role in the immune response and is released during inflammation. Elevated levels of MPO mass in the blood can indicate increased inflammation and oxidative stress, which are associated with cardiovascular diseases.

The measurement of MPO mass is used as a diagnostic tool to evaluate the risk of cardiovascular events, such as heart attacks and strokes. It provides additional information to traditional risk factors and can help in early intervention and prevention strategies.

Normal reference ranges for MPO mass are typically between 0–530 ng/mL. Levels above this range may suggest heightened cardiovascular risk and warrant further clinical evaluation.

Frequently asked questions

What does a high MPO mass level mean?
A high MPO mass level may indicate increased inflammation and oxidative stress, which are associated with a higher risk of cardiovascular diseases.
How is MPO mass measured?
MPO mass is measured through a blood test, where the concentration of myeloperoxidase is quantified in nanograms per milliliter (ng/mL).
  1. 1
    Myeloperoxidase and Cardiovascular DiseaseSource
  2. 2
    Role of Myeloperoxidase in Cardiovascular DiseaseSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy