N-terminal pro-B-type natriuretic peptide (NT-proBNP)
NT-proBNP is a biomarker used to assess heart function and diagnose heart failure by measuring levels of this peptide in the blood.
NT-proBNP helps diagnose and assess the severity of heart failure.
Key facts at a glance
- Units
- pg/mL
- Clinical utility
- diagnostic
- Result kind
- quantitative
- FDA-cleared
- Roche Elecsys NT-proBNP, Abbott ARCHITECT NT-proBNP, Siemens Atellica NT-proBNP
NT-proBNP is a peptide fragment released into the blood when the heart's ventricles are stretched, often due to increased pressure or volume. It is a useful indicator of cardiac dysfunction.
The measurement of NT-proBNP levels is crucial in the diagnosis and management of heart failure. Elevated levels can indicate the presence and severity of heart failure, while decreasing levels may suggest a response to treatment.
Normal NT-proBNP levels are typically between 125–450 pg/mL. Levels above this range may suggest heart failure or other cardiac conditions, while levels below may indicate a low risk of heart failure.
Frequently asked questions
What is the normal range for NT-proBNP?
What does a high NT-proBNP level indicate?
Sources
- 1
- 2
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy