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P-Selectin (Soluble)

Published: July 27, 2026Updated: August 25, 2026

P-selectin (soluble) is a biomarker that measures the levels of a protein involved in platelet activation and leukocyte adhesion, which are crucial for blood clotting and inflammation.

Quick summary

P-selectin (soluble) is a marker for platelet activation and inflammation.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

Units
ng/mL
Clinical utility
diagnostic
Result kind
quantitative
FDA-cleared
Roche Soluble P-Selectin, R&D Systems P-Selectin ELISA
interpretation: {"text":"0–50 ng/mL: Indicates normal levels of platelet activation and inflammation.","label":"Normal"}; {"text":">50 ng/mL: Suggests increased platelet activation, which may be associated with thrombotic disorders or inflammatory conditions.","label":"Elevated"}

P-selectin, also known as CD62P, is a cell adhesion molecule found in platelets and endothelial cells. It plays a key role in the early stages of blood coagulation by mediating the interaction between platelets and leukocytes.

Elevated levels of soluble P-selectin in the blood can indicate increased platelet activation and may be associated with thrombotic disorders, such as deep vein thrombosis and cardiovascular diseases.

The measurement of soluble P-selectin is useful in diagnosing and monitoring conditions related to abnormal platelet function and inflammation.

Frequently asked questions

What conditions can cause elevated P-selectin levels?
Elevated P-selectin levels can be caused by thrombotic disorders, cardiovascular diseases, and inflammatory conditions.
How is the P-selectin test performed?
The test involves a blood draw, and the levels of soluble P-selectin are measured using immunoassays.
  1. 1
    P-Selectin and Cardiovascular DiseaseSource
  2. 2
    Role of P-Selectin in Platelet FunctionSource

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy