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Vascular Endothelial Growth Factor (VEGF)

Published: July 27, 2026Updated: August 25, 2026

VEGF is a signaling protein that promotes the growth of new blood vessels (angiogenesis) and is often elevated in various types of cancer.

Quick summary

VEGF is a biomarker that indicates angiogenesis and is often elevated in cancer.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

Units
pg/mL
Clinical utility
diagnostic
Result kind
quantitative
FDA-cleared
Roche VEGF, R&D Systems VEGF ELISA
interpretation: {"text":"VEGF levels below 0 pg/mL are not physiologically possible and may indicate a sampling or measurement error.","label":"Low"}; {"text":"VEGF levels above 200 pg/mL may suggest the presence of cancer or other conditions that promote angiogenesis.","label":"High"}

Vascular Endothelial Growth Factor (VEGF) is a crucial protein that stimulates the formation of new blood vessels, a process known as angiogenesis. This process is essential for tumor growth and metastasis, as tumors require an adequate blood supply to grow and spread.

Elevated levels of VEGF are frequently observed in various types of cancer, including breast, lung, and colorectal cancer. Measuring VEGF levels can help in diagnosing cancer and monitoring its progression.

The reference range for VEGF is typically 0–200 pg/mL. Levels above this range may indicate the presence of a tumor or other conditions that stimulate angiogenesis.

Frequently asked questions

What is the normal range for VEGF?
The normal range for VEGF is typically 0–200 pg/mL.
Why is VEGF important in cancer?
VEGF is important in cancer because it promotes angiogenesis, which is essential for tumor growth and metastasis.
  1. 1
    VEGF and CancerSource
  2. 2
    Angiogenesis and Tumor GrowthSource

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

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Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy