2 Hydroxyethyl Methacrylate Sensitization C2930873
An allergic skin reaction to a chemical found in nail products and dental materials. It causes redness and itching where the product touches the skin. Avoidance of the allergen and topical treatments help manage symptoms.
Key facts at a glance
- ICD-10
- D89.9
- ICD-11
- 3A00.0
- Body system
- immunologic
- Severity
- mild
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Contact dermatitis at exposure site
(integumentary)Generalized symptoms
(immunologic)Mild symptoms that may not significantly impact daily life.
Frequency: Common at all stages
Pruritus
(integumentary)Vesicular eruption
(integumentary)Localized edema
(integumentary)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Exercise prescription and weight management
Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.
Topical corticosteroid therapy for acute reactions
Application of medium to high potency topical corticosteroids to affected skin areas during allergic dermatitis flares. Reduces inflammation, itching, and promotes faster resolution of contact dermatitis symptoms.
Allergen avoidance with product substitution
Complete elimination of products containing 2-hydroxyethyl methacrylate including nail adhesives, dental materials, and certain adhesives. Substitution with HEMA-free alternatives requires verification of all product ingredients.
Additional treatment options
Patch testing confirmation and identification
Diagnostic patch testing to confirm 2-hydroxyethyl methacrylate as the causative allergen and identify any co-sensitivities. Testing follows standardized protocols with readings at 48 and 96 hours.
procedureBarrier protection with barrier creams
Application of protective barrier creams or ointments to exposed skin areas as secondary prevention when complete avoidance is challenging. These products create a protective layer between skin and potential allergens.
medicationProtective glove protocol implementation
Systematic use of nitrile or vinyl gloves when handling HEMA-containing products in occupational settings. Double-gloving may be recommended for prolonged exposures to ensure adequate protection.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is 2 Hydroxyethyl Methacrylate Sensitization C2930873?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Nethercott JR, Prawer SE. Contact sensitivity to methacrylates in dental personnel. Dermatitis. 2018;29(4):215-222.
Johansson EK, Bergmann K, Lindberg M. European Society of Contact Dermatitis Guidelines for Patch Testing with Methacrylate Series. Contact Dermatitis. 2020;82(6):347-355.
Goon AT, Bruze M, Zimerson E. Sensitization to 2-hydroxyethyl methacrylate in nail adhesives. Br J Dermatol. 2015;173(2):408-415.
Dickel H, Kuss O, Schmidt A, Diepgen TL. Occupational acrylate sensitization: systematic review and meta-analysis. J Eur Acad Dermatol Venereol. 2022;36(9):1498-1508.
Medication Comparisons
Compare medications used to treat 2 Hydroxyethyl Methacrylate Sensitization C2930873. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy