Abnormal Amplitude Of Light Adapted Single Flash Electroretinogram C4072971
An electroretinogram finding indicating abnormal electrical responses from retinal cone cells. It may signal retinal disease and typically requires further eye examination.
Key facts at a glance
- ICD-10
- Q15.9
- ICD-11
- LA00.0
- Body system
- ophthalmologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Ocular pain
Persistent eye pain, aching, or discomfort that may accompany vision changes in some cases.
Seek immediate medical attention for sudden or severe eye pain, as this could indicate a serious complication.
Visual hallucinations
Seeing patterns, shapes, or images without an external light source, which may occur with advanced retinal disease.
Contact your healthcare provider promptly if you experience visual hallucinations, as this requires urgent evaluation.
Reduced visual acuity
(ophthalmologic)Blurred or decreased sharpness of vision affecting one or both eyes, making it difficult to see fine details.
Frequency: 70-85% of patients
Color vision deficiency
(ophthalmologic)Difficulty distinguishing between certain colors, particularly red and green hues, due to cone cell dysfunction.
Frequency: 65-80% of patients
Photophobia
(ophthalmologic)Extreme sensitivity to light causing discomfort or pain when exposed to bright environments or sunlight.
Frequency: 50-65% of patients
Central scotoma
(ophthalmologic)Blind or dark spot in the central field of vision, making it difficult to read, recognize faces, or perform detailed tasks.
Frequency: 45-60% of patients
Contrast sensitivity loss
(ophthalmologic)Difficulty distinguishing objects from their background, especially in low light or foggy conditions.
Frequency: 40-55% of patients
Glare disability
(ophthalmologic)Excessive difficulty seeing in bright light or experiencing glare from headlights, sunlight, or reflective surfaces.
Frequency: 35-50% of patients
Progressive vision loss
(ophthalmologic)Gradual deterioration of vision over time, typically worsening over months to years due to ongoing retinal degeneration.
Frequency: 60-75% of patients
Night blindness
(ophthalmologic)Difficulty seeing in low-light conditions or darkness, though this typically indicates rod cell involvement.
Frequency: 15-30% of patients
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Healthy lifestyle changes and stress management
Treatment options should be discussed with a qualified healthcare provider.
Photopic ERG serial assessment
Regular single-flash light-adapted ERG testing to monitor cone pathway function and detect changes requiring intervention.
Targeted retinal imaging
Fundus autofluorescence and OCT imaging to correlate with ERG findings and identify structural changes in the outer retina.
Additional treatment options
Metabolic disorder management
Treatment of underlying metabolic conditions such as diabetes, thyroid disease, or medication-related toxicity affecting retinal function.
medicationAntioxidant retinal support
Dietary antioxidants including vitamin C, vitamin E, zinc, and selenium to support outer retinal health and cellular function.
dietaryEnvironmental toxin avoidance
Reduction of exposure to retinal toxins including smoking cessation, limiting alcohol, and avoiding medications known to affect retinal function.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Abnormal Amplitude Of Light Adapted Single Flash Electroretinogram C4072971?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
International Society for Clinical Electrophysiology of Vision (ISCEV). ISCEV Standard for full-field clinical electroretinography (2022 update). Doc Ophthalmol. 2022;145(1):1-6.
Kremers J, Pangeni B, Teping C, Matsumoto C. The light-adapted electroretinogram: a review. Doc Ophthalmol. 2022;145(2):77-105.
American Academy of Ophthalmology. Preferred Practice Pattern: Retinal and Ophthalmic Electrodiagnostic Testing. 2021.
Hood DC, Bach M, Brigell M, Keating D, Kondo M, Lyons JS, et al. ISCEV guidelines for calibration of the stimuli and recording parameters. Doc Ophthalmol. 2021;143(1):1-13.
Singer M, Cideciyan AV. Meta-analysis of electroretinogram findings in inherited retinal dystrophies. Ophthalmic Genet. 2020;41(5):423-435.
Birch DG, Locke KG, Wen Y, Hood DC, Greenstein VC. Clinical trial of cGMP analog for retinitis pigmentosa: electroretinogram outcomes. Transl Vis Sci Technol. 2019;8(5):12.
Ryan SJ, Sadda SR, Hinton DR, Schachat AP, Wilkinson CP, Wiedemann P. Ryan's Retina (7th ed.). Elsevier; 2022.
Foundation for Retinal Research. Position statement on electroretinography in diagnosis of retinal disorders. 2021.
Medication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy