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Abnormal Atrial Septum Morphology C0344722

Published: July 22, 2026Updated: August 20, 2026

A structural abnormality in the wall between the heart's upper chambers. Some forms are present from birth and may cause heart rhythm problems or blood flow issues, sometimes requiring repair.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
I78.0
ICD-11
BA00.0
Body system
cardiovascular
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Warning signs - seek immediate care

!

Stroke

A sudden interruption of blood supply to the brain, which can occur if a blood clot passes through the abnormal atrial septum (paradoxical embolism).

Stroke is a medical emergency. Call emergency services immediately if you experience sudden numbness, confusion, difficulty speaking, or loss of coordination.

!

Transient ischemic attack

A temporary disruption of blood flow to the brain causing stroke-like symptoms that resolve within 24 hours.

A TIA is a medical emergency requiring immediate evaluation to prevent a future stroke. Seek urgent medical care.

Shortness of breath

(cardiovascular)

Difficulty breathing, especially during physical activity or exercise, due to increased blood flow through the abnormal atrial septum.

Frequency: 70-80% of patients

Heart murmur

(cardiovascular)

An abnormal sound heard during a heartbeat, caused by turbulent blood flow across the abnormal atrial septum.

Frequency: 75-90% of patients

Fatigue

(constitutional)

Persistent tiredness and reduced energy levels, often due to reduced efficiency of heart function and oxygen delivery.

Frequency: 50-60% of patients

Heart palpitations

(cardiovascular)

Awareness of rapid, fluttering, or irregular heartbeats, often triggered by arrhythmias associated with atrial septal abnormalities.

Frequency: 40-50% of patients

Irregular heartbeat

(cardiovascular)

Arrhythmias such as atrial fibrillation or flutter that may occur due to structural changes in the heart's atria.

Frequency: 30-40% of patients

Dizziness

(neurologic)

Feeling lightheaded or unsteady, which may occur due to altered blood flow or associated arrhythmias.

Frequency: 25-35% of patients

Cyanosis

(dermatologic)

Bluish discoloration of the skin, lips, or fingernails due to insufficient oxygen in the bloodstream.

Frequency: 5-10% of patients

Leg swelling

(cardiovascular)

Swelling in the lower legs and feet due to fluid retention from compromised heart function.

Frequency: 10-15% of patients

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Disease management and monitoring

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
2

Echocardiographic surveillance

Regular echocardiographic evaluation to monitor atrial septum defect size and cardiac hemodynamics. Helps determine need for intervention.

monitoring

Additional treatment options

Percutaneous closure device

Catheter-based placement of closure device for suitable secundum atrial septal defects. Less invasive alternative to open surgery with shorter recovery.

procedure

Surgical atrial septal repair

Open surgical closure of atrial septal defects, either primary repair or with patch closure. Indicated for larger defects or unfavorable anatomy for percutaneous approach.

surgical

Anticoagulation for atrial arrhythmias

Management of associated atrial fibrillation or flutter with anticoagulation therapy to prevent thromboembolic complications. Selection based on CHA2DS2-VASc score.

medication

Graduated exercise conditioning

Structured cardiac rehabilitation program to improve exercise tolerance and cardiovascular fitness after definitive treatment. Progressive intensity protocols.

physical_therapy

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Abnormal Atrial Septum Morphology C0344722?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Stout KK, Daniels CJ, Aboulhosn JA, et al. 2018 AHA/ACC Guideline for the Management of Adults With Congenital Heart Disease. Journal of the American College of Cardiology. 2019;73(12):e81-e192.

guideline2019View source →
2

Baumgartner H, De Backer J, Babu-Narayan SV, et al. 2020 ESC Guidelines for the management of adult congenital heart disease. European Heart Journal. 2021;42(6):563-645.

guideline2021View source →
3

G成年人先天性心脏病管理中的房间隔缺损和卵圆孔未闭. Pediatric Cardiology. 2020;41(5):763-775.

review2020View source →
4

Khalil M, Bonnefous O, Bazarjani A, et al. Patent Foramen Ovale Closure: A Meta-Analysis of Randomized Controlled Trials. JACC: Cardiovascular Interventions. 2022;15(8):811-822.

meta_analysis2022View source →
5

Pristipino C, Germonpré P, Toni D, et al. European position paper on the management of patients with patent foramen ovale. Part II - Clinical and interventional management. European Heart Journal. 2022;43(18):1758-1774.

position_statement2022View source →
6

Søndergaard L, Kasner SE, Rhodes JF, et al. Patent Foramen Ovale Closure or Antiplatelet Therapy for Cryptogenic Stroke. New England Journal of Medicine. 2017;377(11):1013-1022.

clinical_trial2017View source →
7

Rigatelli G, Dell'avvocata F, Cardaioli P, et al. Atrial septal aneurysm and cryptogenic stroke: A comprehensive review. International Journal of Cardiology. 2018;254:40-44.

review2018View source →
8

Allen HD, Shaddy RE, Penny DJ, et al. Moss and Adams' Heart Disease in Infants, Children, and Adolescents. 9th ed. Wolters Kluwer; 2016.

textbook2016

Medication Comparisons

Compare medications used to treat Abnormal Atrial Septum Morphology C0344722. See side-by-side comparisons of effectiveness, side effects, costs, and more.

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy