Abnormal Bowman Space Morphology C5539506
Changes in the space within the kidney's filtering unit where urine first forms. Can impact kidney function depending on the extent. Treatment supports overall kidney health.
Key facts at a glance
- ICD-10
- N28.9
- ICD-11
- GA00.0
- Body system
- renal
- Severity
- mild
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Decreased Urine Output
Reduced amount of urine produced, indicating potential kidney filtration problems.
Immediately if urine output significantly decreases or stops, as this may indicate acute kidney injury.
Proteinuria
(renal)Excess protein in the urine due to impaired filtration in the kidney's glomeruli, often detected via urine testing.
Frequency: 70-80% of patients
Hematuria
(renal)Presence of blood in the urine, which may appear pink, red, or brown.
Frequency: 40-50% of patients
Peripheral Edema
(renal)Swelling in the legs, ankles, or feet due to fluid retention from reduced kidney function.
Frequency: 30-40% of patients
Hypertension
(cardiovascular)Elevated blood pressure due to altered kidney function affecting fluid and salt balance.
Frequency: 35-45% of patients
Fatigue
(constitutional)Persistent tiredness and reduced energy levels due to anemia or toxin buildup from impaired kidney function.
Frequency: 40-50% of patients
Flank Pain
(renal)Pain on either side of the lower back, where the kidneys are located, often dull or aching.
Frequency: 10-15% of patients
Nausea and Vomiting
(gastrointestinal)Feeling sick to the stomach or vomiting due to toxin buildup from reduced kidney function.
Frequency: 10-20% of patients
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Renal disease management
Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.
Urinalysis and imaging follow-up
Regular urine analysis to detect proteinuria or hematuria combined with periodic renal ultrasound to monitor Bowman space morphology changes.
Anti-inflammatory diet
Dietary approach emphasizing omega-3 fatty acids, antioxidants, and reduced inflammatory foods to support renal tissue health and reduce space abnormalities.
Additional treatment options
Hydration optimization
Appropriate fluid intake tailored to individual needs, balancing adequate hydration with avoiding overhydration that could stress kidney structures.
lifestyleAngiotensin receptor blockers
ARBs may be used when ACE inhibitors are not tolerated to help manage intraglomerular pressure and protect Bowman space integrity.
medicationRenal biopsy evaluation
In cases of progression, kidney biopsy may be performed to determine underlying etiology and guide more targeted treatment approaches.
procedureWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Abnormal Bowman Space Morphology C5539506?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Heinz E. Rennert, Matthias B. Classification of Glomerular Diseases. In: Jennette JC, Olson JL, Schwartz MM, Silva FG, editors. Heptinstall's Pathology of the Kidney. 7th ed. Philadelphia: Lippincott Williams & Wilkins; 2015.
Kambham N, Markowitz GS, Valeri AM, Lin J, D'Agati VD. Obesity-related glomerulopathy: an emerging epidemic. Kidney Int. 2001;59(4):1498-1509.
Fogo AB, Kashgarian M. Diagnostic Atlas of Renal Pathology. 3rd ed. Philadelphia: Elsevier; 2017.
Sethi S, D'Agati VD, Nast CC, et al. A proposal for standardized grading of morphologic changes in glomerular diseases. Kidney Int Rep. 2022;7(5):1099-1109.
Kidney Disease: Improving Global Outcomes (KDIGO) Glomerular Diseases Work Group. KDIGO 2021 Guideline for the Management of Glomerular Diseases. Kidney Int. 2021;100(4S):S1-S276.
Tesch GH. Review: Pathogenesis of diabetic nephropathy. Front Endocrinol (Lausanne). 2023;14:1147665.
Walker PD, Cavallo T, Bonsib SM. Diagnostic Pathology: Kidney Diseases. 2nd ed. Philadelphia: Elsevier; 2018.
Wiggins RC. The spectrum of podocytopathies: a unifying view of glomerular diseases. Kidney Int. 2007;71(12):1205-1214.
Berden AE, Ferrario F, Hagen EC, et al. Histopathological classification of ANCA-associated glomerulonephritis. J Am Soc Nephrol. 2010;21(10):1628-1636.
Lusco MA, Fogo AB, Najafian B, Alpers CE. AJKD Atlas of Renal Pathology: Glomerular diseases with crescent formation. Am J Kidney Dis. 2016;68(4):e17-e19.
Medication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy