Abnormal Breast Tissue Biospecimen Cn381913
An abnormal result from breast tissue sample testing. Affects individuals undergoing breast biopsy or specimen analysis. Outlook depends on findings.
Key facts at a glance
- ICD-10
- N94.9
- ICD-11
- GA00.0
- Body system
- reproductive
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Breast lump
A palpable mass or thickening in the breast tissue that may feel different from surrounding tissue.
Seek immediate medical attention if the lump feels hard, is fixed to underlying tissue, or is accompanied by skin changes.
Nipple discharge
Fluid leaking from the nipple that may be clear, bloody, or milky in appearance.
Seek prompt medical evaluation if discharge is bloody, spontaneous, or occurs without squeezing.
Skin changes on breast
Dimpling, puckering, redness, or thickening of the breast skin that may resemble an orange peel texture.
Urgent medical evaluation is needed for persistent skin changes, especially with warmth and swelling.
Breast tenderness
(reproductive)Localized pain or discomfort in one or both breasts, often described as aching or throbbing.
Frequency: 60-70% of patients
Breast swelling
(reproductive)Enlargement or feeling of fullness in all or part of the breast, often accompanied by tightness.
Frequency: 70-80% of patients
Nipple inversion
(reproductive)Nipple turning inward or becoming flattened when it previously protruded normally.
Frequency: 20-30% of patients
Axillary lymph node swelling
(lymphatic)Enlarged lymph nodes in the armpit area that may feel like small, firm lumps.
Frequency: 30-40% of patients
Breast heaviness
(reproductive)A feeling of weight or pressure in the breast that may be constant or intermittent.
Frequency: 50-60% of patients
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Enhanced imaging surveillance
Regular follow-up with advanced imaging techniques such as mammography, ultrasound, or MRI to monitor any changes in abnormal breast tissue. The frequency of imaging depends on clinical findings and risk assessment.
Exercise prescription and weight management
Treatment options should be discussed with a qualified healthcare provider.
Core needle biopsy
Minimally invasive tissue sampling procedure to obtain cellular material for histopathological analysis. This helps determine the nature of the abnormal tissue and guides further management decisions.
Additional treatment options
Surgical excision biopsy
Surgical removal of suspicious tissue for both diagnostic and therapeutic purposes when less invasive methods are inconclusive or when there is concern for malignancy.
surgicalRisk reduction lifestyle modifications
Adoption of healthy lifestyle habits including maintaining normal body weight, limiting alcohol intake, and regular physical exercise to potentially reduce progression risk of abnormal findings.
lifestyleAnxiety management support
Counseling and psychological support to address anxiety and distress associated with abnormal breast tissue findings and awaiting diagnostic results.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Abnormal Breast Tissue Biospecimen Cn381913?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
College of American Pathologists. Protocol for the Examination of Resection Specimens from Patients with Invasive Carcinoma of the Breast. Version 4.2.0.1. CAP Cancer Protocol. 2023.
National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines in Oncology: Breast Cancer. Version 4.2023. NCCN Guidelines. 2023.
WHO Classification of Tumours Editorial Board. Breast Tumours. 5th Edition. WHO Classification of Tumours Series, Volume 2. International Agency for Research on Cancer. 2019.
American Society of Breast Surgeons. Position Statement on Breast Cancer Follow-Up in the Physician Office Setting. ASBrS. 2022.
Dillon MF, Shah BA, Brogi E, Bosen J. Update on the Diagnosis and Management of Breast Lesions: A Review for Pathologists and Clinicians. Advances in Anatomic Pathology. 2021;28(4):215-230.
Allison KH, Partridge AH, Lange J, et al. Consensus Conference on Breast Cancer: Pathology and Biospecimen Reporting. Archives of Pathology & Laboratory Medicine. 2020;144(5):567-576.
Wang M, Chen H, Wu Y, et al. Diagnostic Accuracy of Core Needle Biopsy versus Open Surgical Biopsy for Breast Lesions: A Systematic Review and Meta-Analysis. Annals of Surgical Oncology. 2022;29(8):5154-5167.
Lester SC, Bose S, Chen YY, et al. Protocol for the Examination of Biopsy Specimens from Patients with Breast Lesions. In: WHO Classification of Tumours of the Breast. 5th Edition. IARC Press. 2019:14-18.
Sabel MS, Kunz LP, Gabram SG, et al. Clinical Outcomes of Vacuum-Assisted Breast Biopsy for Atypical Ductal Hyperplasia: A Prospective Study. Annals of Surgical Oncology. 2020;27(9):3405-3414.
American Cancer Society. Breast Cancer Facts & Figures 2022-2023. Atlanta: American Cancer Society, Inc. 2022.
Medication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy