Abnormal Circulating Eicosanoid Concentration C4072901
Abnormal levels of eicosanoids, which are signaling molecules involved in inflammation and immune responses. It can affect various body systems and treatment addresses the underlying inflammatory condition.
Key facts at a glance
- ICD-10
- E88.9
- ICD-11
- 5A00.0
- Body system
- metabolic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Chest discomfort
Pressure, tightness, or aching in the chest area that may be related to altered eicosanoid effects on coronary blood vessels.
Seek immediate medical attention if chest pain is severe, crushing, or accompanied by shortness of breath, sweating, or radiating pain to arm/jaw.
Shortness of breath
Difficulty breathing or feeling breathless, which may relate to altered eicosanoid effects on bronchial tubes and lung function.
Seek immediate care if shortness of breath is sudden, severe, or occurs at rest.
Persistent fatigue
(constitutional)Generalized tiredness and lack of energy that does not improve with rest, often due to altered inflammatory signaling from abnormal eicosanoids.
Frequency: 70-80% of patients
Frequent headaches
(neurologic)Recurring headaches ranging from mild to moderate intensity, potentially related to altered prostaglandin affecting blood vessels in the brain.
Frequency: 50-60% of patients
Joint pain and stiffness
(musculoskeletal)Aching or painful joints, particularly in the morning or after periods of inactivity, associated with inflammatory eicosanoid imbalances.
Frequency: 45-55% of patients
Elevated blood pressure
(cardiovascular)Frequency: 40-50% of patients
Abdominal discomfort
(gastrointestinal)Generalized stomach pain, bloating, or digestive disturbances linked to inflammatory mediators affecting gut function.
Frequency: 20-30% of patients
Skin inflammation
(dermatologic)Redness, itching, or rash-like patches on the skin resulting from altered leukotriene and prostaglandin activity affecting dermal blood vessels.
Frequency: 15-20% of patients
Cognitive difficulties
(neurologic)Problems with concentration, memory, or mental clarity that may result from chronic inflammatory eicosanoid effects on neural function.
Frequency: 5-10% of patients
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Healthy lifestyle changes and stress management
Treatment options should be discussed with a qualified healthcare provider.
Omega-3 fatty acid supplementation
Dietary modification to increase omega-3 intake through food sources such as fatty fish, flaxseeds, and walnuts. Omega-3 fatty acids help restore normal eicosanoid balance by providing anti-inflammatory precursors.
Anti-inflammatory medication therapy
Pharmacological approach using anti-inflammatory agents to modulate eicosanoid production and restore normal circulating concentrations. Treatment targets the underlying inflammatory process.
Additional treatment options
Anti-inflammatory lifestyle modification
Implementation of stress reduction techniques, regular exercise, and avoidance of pro-inflammatory environmental triggers. These changes help regulate the body's natural eicosanoid production pathways.
lifestyleHerbal and botanical therapy
Use of traditional anti-inflammatory herbs such as turmeric, ginger, and boswellia to support eicosanoid balance through natural mechanisms.
complementaryEicosanoid level monitoring
Regular laboratory assessment of circulating eicosanoid concentrations to track treatment response and adjust interventions as needed.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Abnormal Circulating Eicosanoid Concentration C4072901?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Ricciotti E, FitzGerald GA. Prostaglandins and inflammation. Arterioscler Thromb Vasc Biol. 2011;31(5):986-1000.
Ahmad SF, Zaibi MA, Al-Ayadhi L. Eicosanoids and their role in inflammatory diseases. Inflamm Res. 2015;64(11):853-865.
Wang D, DuBois RN. Eicosanoids and cancer. Nat Rev Cancer. 2016;16(3):131-144.
American Diabetes Association. Standards of Medical Care in Diabetes—2020. Diabetes Care. 2020;43(Suppl 1):S1-S212.
Böhm E, Sturm GJ, Lippe R, et al. Eicosanoid profiles in patients with metabolic syndrome. J Lipid Res. 2014;55(11):2255-2265.
Capra V, Bäck M, Barbieri SS, et al. Eicosanoids and their drugs in cardiovascular diseases: focus on atherosclerosis and stroke. Med Res Rev. 2013;33(2):364-405.
American Heart Association. Omega-3 fatty acids and cardiovascular disease. Circulation. 2019;139:e1-e22.
FitzGerald GA. Eicosanoids. In: Melmed S, et al., eds. Williams Textbook of Endocrinology. 14th ed. Elsevier; 2020:chap 3.
World Health Organization. Global Action Plan for the Prevention and Control of Noncommunicable Diseases 2013-2020. Geneva: WHO; 2013.
Medication Comparisons
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy