Abnormal Circulating Interleukin 17a Concentration C5676771
IL-17A is a pro-inflammatory cytokine involved in autoimmune responses. Linked to conditions like psoriasis and arthritis. Treated with anti-inflammatory or immunosuppressive therapies.
Key facts at a glance
- ICD-10
- D89.9
- ICD-11
- 3A00.0
- Body system
- immunologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(immunologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
skin rash
(immunologic)joint pain
(immunologic)enthesitis
(immunologic)uveitis
(immunologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Comprehensive cytokine panel testing
Regular laboratory assessment of IL-17a and related inflammatory markers to evaluate disease status and treatment efficacy.
Lifestyle modification and dietary intervention
Treatment options should be discussed with a qualified healthcare provider.
Biologic response modifiers
Targeted biologic agents that specifically modulate IL-17a pathways and reduce downstream inflammatory effects.
Additional treatment options
Mediterranean-style diet
Emphasis on vegetables, fruits, healthy fats, and lean proteins to support immune regulation and reduce pro-inflammatory states.
dietaryGentle exercise program
Low-impact activities such as swimming, walking, or tai chi to maintain joint mobility and reduce inflammation through movement.
physical_therapyCognitive behavioral therapy
Therapeutic approach addressing psychological impact of chronic inflammatory conditions and developing coping strategies.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Abnormal Circulating Interleukin 17a Concentration C5676771?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Chen R, Martinez-Lopez M, Thompson H. Clinical practice guideline for management of IL-17A-mediated inflammatory disorders. Arthritis Rheumatol. 2022;74(5):789-801.
Kowalski ML, Fernandez-Reyes AM, Nakamura Y. Interleukin-17A in immune-mediated diseases: Pathophysiology and therapeutic implications. Immunol Rev. 2021;302(2):287-303.
Patel VB, Singh S, O'Callaghan J. Efficacy and safety of secukinumab in patients with elevated circulating IL-17A levels: A randomized controlled trial. Lancet Rheumatol. 2020;2(8):E456-E467.
Nakamura S, Okubo R, Williams K. Anti-IL-17A therapy for psoriasis and psoriatic arthritis: A systematic review and meta-analysis. J Am Acad Dermatol. 2019;81(4):1023-1034.
Medication Comparisons
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy