Abnormal Circulating Iron Concentration C0235760
This involves abnormal iron levels in the blood, which can lead to conditions like anemia when too low or organ damage when too high. Management includes dietary changes, medications, or procedures to regulate iron levels.
Key facts at a glance
- ICD-10
- D64.9
- ICD-11
- 3A00.0
- Body system
- hematologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Chest pain
Sharp or pressure-like chest discomfort that may indicate serious cardiac strain or underlying heart disease related to iron abnormalities.
Seek emergency medical care immediately if chest pain is severe, radiates to the arm/jaw, or is accompanied by shortness of breath.
Fatigue and weakness
(constitutional)Persistent tiredness and lack of energy that interferes with daily activities, often due to impaired oxygen transport from abnormal iron levels.
Frequency: 70-80% of patients
Pale skin pallor
(dermatologic)Unusually light skin tone, particularly noticeable in the face, lips, and nail beds, caused by reduced hemoglobin.
Frequency: 60-70% of patients
Shortness of breath
(respiratory)Difficulty breathing or feeling winded during minimal exertion, resulting from reduced oxygen-carrying capacity of blood.
Frequency: 40-50% of patients
Dizziness and lightheadedness
(neurologic)Feeling faint, woozy, or unsteady, often worsening when standing up quickly due to altered blood flow.
Frequency: 30-40% of patients
Brittle or ridged nails
(dermatologic)Nails that break, split, or develop ridges easily, often appearing spoon-shaped (koilonychia) in iron deficiency.
Frequency: 25-35% of patients
Rapid heart rate
(cardiovascular)Elevated resting heart rate or heart palpitations as the heart works harder to compensate for reduced oxygen delivery.
Frequency: 15-20% of patients
Abdominal discomfort
(gastrointestinal)Pain or aching in the abdominal region, which may be associated with organ involvement in iron overload conditions.
Frequency: 10-15% of patients
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Healthy lifestyle changes and stress management
Treatment options should be discussed with a qualified healthcare provider.
Iron supplementation therapy
Oral iron replacement to address iron deficiency anemia and restore normal circulating iron levels. Iron stores typically take several months to fully replenish.
Iron-rich dietary modification
Increased consumption of heme iron sources such as lean meats, poultry, and fish, along with non-heme iron sources including legumes, fortified cereals, and leafy greens.
Additional treatment options
Phlebotomy for iron overload
Therapeutic blood removal for conditions causing excessive iron accumulation, such as hereditary hemochromatosis. Regular sessions gradually deplete iron stores.
procedureIron chelation therapy
Pharmacological agents that bind excess iron for urinary excretion in patients with iron overload who cannot tolerate phlebotomy. Reserved for secondary hemochromatosis.
medicationIron studies monitoring
Serial measurement of serum iron, ferritin, transferrin saturation, and total iron-binding capacity to guide treatment decisions and prevent overcorrection.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Abnormal Circulating Iron Concentration C0235760?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
World Health Organization. Guideline: Iron supplementation in women of reproductive age. Geneva: WHO; 2018.
World Health Organization. Daily iron supplementation in infants and children. Geneva: WHO; 2016.
Bacon BR, Adams PC, Kowdley KV, Powell LW, Tavill AS. Diagnosis and management of hemochromatosis: 2011 practice guideline by the American Association for the Study of Liver Diseases. Hepatology. 2011;53(3):1-25.
European Association for the Study of the Liver. EASL Clinical Practice Guidelines for HFE Hemochromatosis. J Hepatol. 2022;77(2):479-496.
Cappellini MD, Comin-Colet J, de Francisco A, et al. Iron deficiency across chronic inflammatory conditions: International expert opinion on definition, diagnosis, and management. Am J Hematol. 2017;92(10):1068-1078.
Powers JM, Buchanan GR. Diagnosis and management of iron deficiency anemia. Hematol Oncol Clin North Am. 2014;28(4):729-745.
Hoffbrand AV, Moss PAH. Essential Haematology. 7th ed. Wiley-Blackwell; 2021.
Fernandez-Gaxiola AC, De-Regil LM. Intermittent iron supplementation for reducing anaemia and its associated impairments in adolescent and adult menstruating women. Cochrane Database Syst Rev. 2019;1(1):CD009218.
Stoffel NU, Zeder C, Brittenham GM, Moretti D, Zimmermann MB. Iron absorption from supplements is greater with alternate day than consecutive day dosing in iron-deficient women. Haematologica. 2020;105(5):1232-1239.
Pasricha SR, Tye-Din J, Muckenthaler MU, Swinkels DW. Iron deficiency. Lancet. 2021;397(10270):233-248.
Medication Comparisons
Compare medications used to treat Abnormal Circulating Iron Concentration C0235760. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy