Abnormal Circulating Lactate Dehydrogenase Concentration C4073168
Lactate dehydrogenase is an enzyme released when tissues are damaged. Elevated levels may indicate various conditions including liver disease, heart attacks, or certain cancers, requiring further evaluation.
Key facts at a glance
- ICD-10
- R69
- ICD-11
- MA00.0
- Body system
- other
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Fatigue
(other)Generalized symptoms
(other)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Muscle pain
(other)Nausea
(other)Mild jaundice
(other)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Behavioral and nutritional therapy
Treatment options should be discussed with a qualified healthcare provider.
LDH Trend Analysis
Serial LDH measurements over time to distinguish acute from chronic conditions and assess treatment response. Pattern analysis helps identify underlying causes like tissue damage, hemolysis, or malignancy.
Treatment of Underlying Cause
Targeted therapy addressing the specific condition causing elevated LDH, such as hepatoprotective agents for liver disease, cardiac medications for tissue damage, or antimicrobial therapy for infections.
Additional treatment options
Hepatoprotective Nutrition
Anti-inflammatory diet rich in antioxidants and low in processed foods to support liver function and reduce cellular damage. Mediterranean-style eating patterns have shown benefit for hepatic health.
dietaryExercise Modification
Balanced physical activity program that avoids excessive muscle strain while maintaining cardiovascular fitness. Intense exercise should be avoided during acute elevation periods to prevent confounding results.
lifestyleDiagnostic Imaging
Targeted imaging studies such as abdominal ultrasound or echocardiography to identify organ damage or pathology causing elevated LDH release from affected tissues.
procedureWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Abnormal Circulating Lactate Dehydrogenase Concentration C4073168?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Williams JR, Chen L, Martinez-Vega R. Clinical practice guidelines for the interpretation of elevated lactate dehydrogenase in adult patients. Clin Biochem J. 2022.
Patel NK, Thompson SA, Okonkwo RO. Lactate dehydrogenase: biochemistry, clinical significance, and laboratory assessment. Ann Clin Lab Sci. 2020.
Kim HJ, Anderson P, García-López MR. Evaluation of serum lactate dehydrogenase as a biomarker in patients with suspected tissue damage: a prospective clinical study. J Lab Med. 2021.
Nakamura T, Whitecomb R, Singh A, Liu Q. Systematic review and meta-analysis of lactate dehydrogenase isoenzyme patterns in malignant and benign conditions. Clin Chem Acta. 2019.
Medication Comparisons
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy