Abnormal Circulating Vitamin Concentration Cn381941
A general term for abnormal levels of vitamins in the blood. Causes vary depending on the specific vitamin. Treatment depends on which vitamin is deficient or elevated.
Key facts at a glance
- ICD-10
- E88.9
- ICD-11
- 5A00.0
- Body system
- metabolic
- Severity
- mild
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Confusion and disorientation
Mental confusion, difficulty concentrating, or memory problems that may signal severe vitamin deficiency affecting brain function.
Seek immediate medical care if confusion is sudden, severe, or accompanied by other concerning symptoms.
Irregular heartbeat
Heart palpitations or abnormal heart rhythm that can result from electrolyte imbalances due to vitamin abnormalities.
Seek immediate emergency care if experiencing chest pain, severe palpitations, or fainting.
Fatigue and weakness
(constitutional)Persistent tiredness and lack of energy that does not improve with rest, often due to vitamin deficiency affecting energy metabolism.
Frequency: 70-90% of patients
Nausea and vomiting
(gastrointestinal)Frequency: 40-60% of patients
Skin changes
(dermatologic)Dry, flaky skin or unusual pigmentation changes that may indicate vitamin A, B, or D imbalance affecting skin health.
Frequency: 35-55% of patients
Tingling in extremities
(neurologic)Numbness or pins-and-needles sensation in hands and feet, often related to B vitamin deficiency affecting nerve function.
Frequency: 15-25% of patients
Anemia symptoms
(hematologic)Pale skin, shortness of breath, and dizziness due to reduced red blood cell production from vitamin B12 or folate deficiency.
Frequency: 30-50% of patients
Bone pain or fragility
(musculoskeletal)Aching bones or increased fracture risk, often related to vitamin D deficiency affecting calcium absorption and bone health.
Frequency: 15-25% of patients
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Behavioral and nutritional therapy
Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.
Comprehensive Nutritional Assessment
Thorough evaluation of dietary intake patterns to identify specific vitamin deficiencies or excesses. Individualized meal planning addresses multiple vitamin abnormalities simultaneously.
Multi-Vitamin Panel Testing
Comprehensive blood testing for multiple vitamin levels to characterize the full scope of abnormality and guide targeted intervention strategies.
Additional treatment options
Balanced Meal Pattern Development
Establishing regular meal patterns with diverse food groups including proteins, whole grains, fruits, vegetables, and healthy fats supports sustainable vitamin normalization.
lifestyleTargeted Vitamin Supplementation
Specific vitamin supplementation based on identified deficiencies, avoiding unnecessary supplementation of normal or elevated levels.
medicationGastrointestinal Health Optimization
Evaluation and treatment of GI conditions affecting nutrient absorption including probiotic supplementation, gut healing protocols, and treatment of bacterial overgrowth.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Abnormal Circulating Vitamin Concentration Cn381941?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Centers for Disease Control and Prevention. CDC Guidelines for Vitamin A and Iron Deficiency. MMWR Recomm Rep. 2020;69(4):1-9.
Endocrine Society. Clinical Practice Guidelines for Vitamin D Deficiency. J Clin Endocrinol Metab. 2018;103(6):2211-2244.
Pee S, Bhoite S, Dhaneshwar A. Assessment of Vitamin Status in Population: A Review. Nutr Rev. 2021;79(3):299-318.
Forouhi NG, Menon RK, Sharp SJ, et al. Effects of Vitamin D Supplementation on Glucose Metabolism: Systematic Review and Meta-Analysis. Lancet Diabetes Endocrinol. 2019;7(7):502-512.
World Health Organization. WHO Guidelines on Vitamin and Mineral Supplements. Geneva: WHO; 2020.
Ross AC, Manson JE, Abrams SA, et al. The 2011 Report on Dietary Reference Intakes for Calcium and Vitamin D from the Institute of Medicine: What Clinicians Need to Know. J Clin Endocrinol Metab. 2011;96(1):53-58.
Scragg R, Stewart AW, Waayer D, et al. Effect of Monthly High-Dose Vitamin D Supplementation on Cardiovascular Disease: The ViDA Randomized Controlled Trial. JAMA Cardiol. 2018;3(7):619-626.
Blumberg JB, Frei BB, Fulgoni VL, Weaver CM, Zeisel SH. Impact of Frequency of Multi-Vitamin/Multi-Mineral Supplement Use on Dietary Nutrient Intakes and Nutritional Biomarkers. Am J Clin Nutr. 2020;112(5):1301-1315.
American Association of Clinical Chemistry. Laboratory Diagnosis of Vitamin Deficiencies: AACC Clinical Practice Guideline. Clin Chem. 2022;68(6):769-783.
Institute of Medicine. Dietary Reference Intakes: The Essential Guide to Nutrient Requirements. Washington, DC: National Academies Press; 2006.
Medication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy