Abnormal Coronary Artery Physiology C4476812
Abnormal coronary artery physiology means the coronary arteries are not functioning normally, even if structurally normal. This can affect blood flow to the heart during exertion or stress. Management includes medications, lifestyle modifications, and sometimes additional testing or procedures.
Key facts at a glance
- ICD-10
- I78.0
- ICD-11
- BA00.0
- Body system
- cardiovascular
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Exertional chest discomfort
Radiating arm pain
Chest discomfort or palpitations
(cardiovascular)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Exertional dyspnea
(cardiovascular)Nausea with exertion
(cardiovascular)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Anti-ischemic pharmacotherapy
Medications to improve coronary blood flow, reduce myocardial oxygen demand, and address functional abnormalities in coronary physiology.
Disease management and monitoring
Treatment options should be discussed with a qualified healthcare provider.
Cardiac risk factor modification
Smoking cessation, blood pressure control, and stress management to improve coronary artery function and reduce physiological abnormalities.
Additional treatment options
Coronary physiology assessment
Invasive fractional flow reserve or non-invasive stress testing to precisely characterize coronary artery physiology and guide treatment.
procedureSupervised exercise training
Graduated exercise program under cardiac supervision to improve endothelial function and optimize coronary physiology.
physical_therapyPlant-based dietary intervention
Whole-food plant-based diet to reduce systemic inflammation and improve vascular endothelial function.
dietaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Abnormal Coronary Artery Physiology C4476812?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Kern MJ, Seto AH,的非WM. ACC/AHA/SCAI guidelines for coronary physiology assessment. Circulation. 2023.
Pijls NH, De Bruyne B, Smith CR. Coronary physiology and fractional flow reserve: a comprehensive review. Eur Heart J. 2021.
De Bruyne B, Piroth Z, Tonino PA, et al. Fractional flow reserve versus angiography for guiding PCI. N Engl J Med. 2018.
Johnson NP, Toth GG, Lai D, et al. Prognostic value of fractional flow reserve: meta-analysis of 22 trials. JACC Cardiovasc Interv. 2020.
Medication Comparisons
Compare medications used to treat Abnormal Coronary Artery Physiology C4476812. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy