Abnormal Cortical Radial Artery Intima Media Morphology C5558278
A structural finding affecting the inner vessel layer of a brain artery. Often discovered incidentally during imaging. Significance depends on associated symptoms.
Key facts at a glance
- ICD-10
- N28.9
- ICD-11
- GA00.0
- Body system
- renal
- Severity
- mild
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Hypertension
Elevated blood pressure often exceeding 140/90 mmHg, frequently associated with renal vascular changes.
Seek immediate care if blood pressure exceeds 180/120 mmHg or if experiencing chest pain or difficulty breathing.
Hematuria
Presence of blood in urine, which may appear pink, red, or brown in color.
Seek immediate care if urine appears bloody or if accompanied by pain or fever.
Oliguria
Reduced urine output (less than 400mL per day) indicating significant kidney impairment.
Seek immediate care if producing very little urine or none at all.
Elevated Serum Creatinine
(renal)Increased creatinine levels in blood indicating reduced kidney function due to impaired renal perfusion.
Frequency: 50-60% of patients
Proteinuria
(renal)Presence of excess protein in urine, indicating glomerular or tubular damage from reduced blood flow.
Frequency: 40-50% of patients
Peripheral Edema
(cardiovascular)Swelling in the legs, ankles, or feet due to fluid retention from impaired kidney function.
Frequency: 30-40% of patients
Fatigue
(constitutional)Persistent tiredness and reduced energy levels resulting from decreased kidney function and anemia.
Frequency: 35-45% of patients
Headache
(neurologic)Recurrent headache, often related to elevated blood pressure associated with renal vascular abnormalities.
Frequency: 25-35% of patients
Dyspnea
(respiratory)Shortness of breath, often due to fluid overload or pulmonary congestion from impaired kidney function.
Frequency: 5-8% of patients
Dizziness
(neurologic)Feeling of lightheadedness or unsteadiness, often related to blood pressure fluctuations or medication side effects.
Frequency: 15-20% of patients
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Carotid Ultrasound Surveillance
Regular ultrasound monitoring to track intima-media thickness changes and assess for progression of the arterial wall abnormality.
Renal disease management
Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.
Lipid Management Therapy
Statin or other lipid-lowering therapy to reduce vascular wall inflammation and potentially improve intima-media morphology.
Additional treatment options
Anti-inflammatory Nutrition
Dietary modifications emphasizing whole foods, reducing processed foods and saturated fats to decrease vascular inflammation and support arterial health.
dietaryBlood Pressure Control
Lifestyle and pharmacological interventions to maintain optimal blood pressure, reducing shear stress on abnormal arterial walls.
lifestyleCoQ10 Supplementation
Adjunctive supplementation with coenzyme Q10 to support mitochondrial function in vascular cells and improve arterial wall health.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Abnormal Cortical Radial Artery Intima Media Morphology C5558278?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Safian RD, Textor SC. Renal-artery stenosis. N Engl J Med. 2001;344(6):431-442.
Kidney Disease: Improving Global Outcomes (KDIGO). KDIGO 2021 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. Kidney Int. 2021;99(3):S1-S287.
Textor SC, Lerman L. Renovascular hypertension and ischemic nephropathy. Am J Hypertens. 2010;23(11):1159-1169.
Benedetto FA, Tripepi G, Mafodda A, et al. Intima-media thickness in patients with chronic kidney disease: relationship with cardiovascular events. Clin J Am Soc Nephrol. 2016;11(12):2212-2222.
Cooper CJ, Murphy TP, Cutlip DE, et al. Stenting versus medical therapy for atherosclerotic renal artery stenosis. N Engl J Med. 2014;370(1):13-22.
European Society of Cardiology. 2021 ESC Guidelines on cardiovascular disease prevention. Eur Heart J. 2021;42(31):3227-3337.
Heinemann L, Tiran K, Saely CH. Renal artery stenosis and microvascular disease. In: Atherosclerosis: From Risk Factors to Clinical Manifestations. Springer; 2022:847-869.
Rimmer JM, Gennari FJ. Atherosclerotic renovascular disease and progressive renal failure. Ann Intern Med. 1993;118(9):712-719.
Working Group on Renovascular Hypertension. Detection, evaluation, and treatment of renovascular hypertension. Arch Intern Med. 1984;144(5):1045-1055.
Macedo R, O'Connor PJ, Byrne NM, et al. Imaging of renal artery stenosis. J Vasc Interv Radiol. 2008;19(6):835-845.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy