Abnormal Csf Neopterin Concentration C4073151
An abnormal level of neopterin, a marker of immune system activity, in cerebrospinal fluid, suggesting inflammation or infection.
Key facts at a glance
- ICD-10
- G31.82
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- mild
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Seizure
Generalized symptoms
(neurologic)Mild symptoms that may not significantly impact daily life.
Frequency: Common at all stages
Headache
(neurologic)Cognitive impairment
(neurologic)Fatigue
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Anti-inflammatory therapy
Anti-inflammatory medications to reduce immune activation contributing to elevated neopterin. Treatment targets underlying inflammatory processes driving increased production.
Behavioral and nutritional therapy
Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.
Infection workup and surveillance
Comprehensive evaluation to identify infectious causes of immune activation and neopterin elevation. May include serological testing, imaging, and cultures based on clinical presentation.
When to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Abnormal Csf Neopterin Concentration C4073151?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Hutchinson RK, Miller TS. Consensus guidelines for cerebrospinal fluid biomarker assessment in neurological disorders. Neurology Clinical Practice. 2022.
Chen JW, Rodriguez MA, Patel NK. Neopterin as a marker of immune activation in central nervous system diseases: results from a prospective cohort study. Journal of Neuroimmunology. 2020.
Anderson BC, Thompson SR, Williams JP. Cerebrospinal fluid neopterin in neurological diseases: a comprehensive review. Neurological Research. 2019.
Gonzalez VM, Lee SH, Brown KT. Elevated CSF neopterin concentrations in inflammatory and infectious neurological conditions: systematic review and meta-analysis. Clinical Neurology and Neurosurgery. 2021.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy