Abnormal Energy Expenditure C4022949
A finding that the body burns calories at an abnormal rate. It can be associated with thyroid disorders or metabolic conditions and is evaluated and managed based on cause.
Key facts at a glance
- ICD-10
- E88.9
- ICD-11
- 5A00.0
- Body system
- metabolic
- Severity
- mild
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Severe metabolic disturbance
Dangerous imbalance in body chemicals causing confusion, vomiting, or loss of consciousness.
Seek emergency care immediately if experiencing confusion, severe vomiting, or loss of consciousness.
Shortness of breath
Difficulty breathing or feeling breathless with minimal exertion.
Seek immediate care if shortness of breath occurs at rest or is accompanied by chest pain.
Persistent fatigue
(constitutional)Feeling unusually tired or exhausted even after rest, with reduced ability to perform normal activities.
Frequency: 80-90% of patients
Unexplained weight changes
(constitutional)Significant weight gain or loss without changes in diet or exercise routine.
Frequency: 70-80% of patients
Temperature intolerance
(metabolic)Feeling unusually cold or hot compared to others in the same environment.
Frequency: 50-60% of patients
Abnormal heart rate
(cardiovascular)Heart beats faster or slower than normal, sometimes with palpitations or fluttering sensation.
Frequency: 40-50% of patients
Muscle weakness
(musculoskeletal)Reduced muscle strength making it difficult to lift objects or climb stairs.
Frequency: 45-55% of patients
Excessive sweating
(dermatologic)Unusually heavy sweating even during rest or in cool environments.
Frequency: 40-50% of patients
Difficulty concentrating
(neurologic)Trouble focusing, brain fog, or mental fatigue affecting daily tasks.
Frequency: 25-35% of patients
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Behavioral and nutritional therapy
Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.
Metabolic comprehensive assessment
Complete metabolic evaluation including thyroid function, adrenal studies, and body composition analysis to identify underlying causes of altered energy expenditure.
Individualized nutrition planning
Calorie and macronutrient prescription based on measured resting metabolic rate to achieve healthy weight and optimize energy balance.
Additional treatment options
Activity counseling program
Structured physical activity recommendations based on metabolic assessment to increase energy expenditure appropriately for the patient's condition.
lifestyleIndirect calorimetry follow-up
Serial measurements of energy expenditure to track metabolic changes and adjust intervention strategies accordingly.
monitoringBehavioral assessment
Evaluation for eating disorders or psychological factors that may contribute to abnormal energy expenditure patterns.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Abnormal Energy Expenditure C4022949?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
American Diabetes Association. Standards of Medical Care in Diabetes-2020. Diabetes Care. 2020;43(Suppl 1):S1-S212.
Westerterp KR. Energy metabolism: a new perspective on human obesity. Eur J Clin Nutr. 2020;74(4):559-566.
World Health Organization. WHO Guidelines on Physical Activity and Sedentary Behaviour. Geneva: WHO; 2020.
Tomlinson DJ, Erskine RM, Morse CI, Winwood K. The impact of obesity on skeletal muscle strength and structure through adaptation changes in muscle: a systematic review and meta-analysis. Obes Rev. 2021;22(2):e13182.
Rosenstock J, Wysham C, Frías JP, et al. Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist tirzepatide in patients with type 2 diabetes (SURPASS-1). Lancet. 2021;398(10295):143-155.
American Association of Clinical Endocrinologists. American Association of Clinical Endocrinologists Comprehensive Type 2 Diabetes Management Algorithm 2020. Endocr Pract. 2020;26(8):1079-1113.
Hall KD, Heymsfield SB, Kemnitz JW, Klein S, Schoeller DA, Speakman JR. Energy balance and its components: implications for weight management. Am J Clin Nutr. 2012;96(2):251-262.
Ensrud KE, Crandall CJ. Osteoporosis: fragility fractures and the diagnosis of osteoporosis. JAMA. 2022;327(19):1928-1929.
Hall JE, Hall ME. Guyton and Hall Textbook of Medical Physiology. 14th ed. Philadelphia: Elsevier; 2020.
Speakman JR, Hambly C. Energy expenditure and body composition in laboratory mice. Physiol Behav. 2016;164(Pt A):239-250.
Medication Comparisons
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If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy