Abnormal Femoral Metaphysis Morphology C4025040
An abnormality in the widened portion of the femur near the growth plate. It primarily affects children during bone development and may require treatment depending on impact on growth.
Key facts at a glance
- ICD-10
- Q79.9
- ICD-11
- LA00.0
- Body system
- musculoskeletal
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Pathological fracture
Bone break occurring with minimal trauma due to weakened structural integrity of the abnormal femoral metaphysis.
Seek immediate medical attention if sudden severe pain, swelling, or inability to bear weight occurs after minor injury.
Compromised circulation
Reduced blood flow to the lower leg due to vascular involvement or compression from severe deformity.
Seek emergency care if experiencing severe pain, pallor, numbness, or coldness in the affected limb.
Femoral metaphyseal deformity
(musculoskeletal)Abnormal shaping or curvature of the distal thigh bone near the knee joint, often visible on imaging studies.
Frequency: 90-100% of patients
Abnormal gait pattern
(musculoskeletal)Unusual walking style often characterized by a waddling or limping movement due to bone deformity.
Frequency: 80-90% of patients
Knee pain
(musculoskeletal)Discomfort or aching sensation in or around the knee joint, often exacerbated by weight-bearing activities.
Frequency: 60-70% of patients
Leg length discrepancy
(musculoskeletal)One leg appears shorter than the other due to asymmetric growth or deformity of the femoral metaphysis.
Frequency: 50-60% of patients
Reduced mobility
(musculoskeletal)Difficulty walking, running, or performing usual physical activities due to structural abnormalities.
Frequency: 55-65% of patients
Knee instability
(musculoskeletal)Feeling that the knee may give way or feel loose, particularly during weight-bearing or directional changes.
Frequency: 40-50% of patients
Muscle weakness
(musculoskeletal)Decreased strength in the quadriceps or surrounding leg muscles due to altered biomechanics.
Frequency: 25-35% of patients
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Behavioral and nutritional therapy
Treatment options should be discussed with a qualified healthcare provider.
Weight-bearing exercise program
A structured physical therapy program focusing on low-impact weight-bearing exercises to strengthen the femoral region and improve bone loading patterns. Progressive resistance training helps promote proper bone remodeling and alignment.
Serial radiographic assessment
Regular imaging follow-up using X-rays or CT scans to monitor morphological changes and assess progression of femoral abnormalities. Enables early detection of deterioration requiring intervention.
Additional treatment options
Corrective osteotomy
Surgical procedure to realign the femoral metaphysis by cutting and repositioning bone segments. Typically reserved for severe cases or when conservative measures fail to prevent functional impairment.
surgicalCalcium and vitamin D supplementation
Adequate calcium and vitamin D intake to support bone health and mineralization. General supplementation guidance as part of comprehensive bone health management.
medicationActivity modification
Guidance on avoiding activities that stress the abnormal femoral metaphysis, including high-impact sports and excessive rotational movements. Ergonomic adjustments for daily activities to reduce mechanical stress.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Abnormal Femoral Metaphysis Morphology C4025040?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
International Society for Clinical Densitometry. Official Positions of the International Society for Clinical Densitometry on skeletal health assessment in children and adults with genetic bone diseases. J Clin Densitom. 2022.
Warman ML, Cormier-Daire V, Hall C, et al. Nosology and classification of genetic skeletal disorders: 2019 revision. Am J Med Genet A. 2019;179(12):2393-2419.
Rimoin DL, Pyeritz RE, Korf B, editors. Emery and Rimoin's Principles and Practice of Medical Genetics and Genomics. 7th ed. Academic Press; 2022.
Bone Health and Osteoporosis Foundation. Clinician's Guide to Prevention and Treatment of Osteoporosis in Genetic Skeletal Disorders. 2020.
Unger S, Ferreira CR, Mortier GR, et al. Nosology of genetic skeletal disorders: 2023 revision. Am J Med Genet A. 2023;191(11):2644-2669.
Ornitz DM, Legeai-Mallet L. Achondroplasia: Development, pathogenesis, and therapy. Dev Dyn. 2017;246(4):291-309.
Hoernschemeyer DG, McAlister JE, Bomar JD, et al. Surgical management of lower extremity deformities in skeletal dysplasias: A multicenter prospective study. J Pediatr Orthop. 2021;41(5):312-320.
Pauli RM, Breed A, Horton VK, Glinski LP. Systematic review of radiographic outcomes in skeletal dysplasia: Meta-analysis of fracture risk. Bone. 2019;127:494-502.
American College of Medical Genetics and Genomics. Clinical practice resource: Genetic testing for skeletal dysplasias. Genet Med. 2021;23(10):1863-1877.
Medication Comparisons
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy