Abnormal Globus Pallidus Morphology C4025706
An abnormality in a brain structure involved in movement control. Changes in this area may be associated with certain movement or neurological disorders.
Key facts at a glance
- ICD-10
- G43.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Dysphagia
Difficulty swallowing that may cause choking or coughing during meals.
Seek immediate care if choking episodes occur or if food frequently gets stuck in throat.
Resting Tremor
(neurologic)Involuntary shaking that occurs when muscles are relaxed, typically starting in the hands or fingers.
Frequency: 60-70% of patients
Muscle Rigidity
(neurologic)Stiffness and resistance in muscles that limits range of motion and causes discomfort.
Frequency: 70-80% of patients
Bradykinesia
(neurologic)Slowness of movement and difficulty initiating voluntary actions.
Frequency: 75-85% of patients
Dysarthria
(neurologic)Speech difficulty characterized by slow, slurred, or soft speech.
Frequency: 40-50% of patients
Dystonia
(neurologic)Involuntary muscle contractions causing repetitive movements or abnormal postures.
Frequency: 35-45% of patients
Cognitive Impairment
(neurologic)Memory difficulties, reduced concentration, and trouble with problem-solving or decision-making.
Frequency: 40-50% of patients
Mood Changes
(neurologic)Development of depression, anxiety, or emotional lability.
Frequency: 35-45% of patients
Chorea
(neurologic)Involuntary, irregular, jerky movements that appear dance-like.
Frequency: 15-25% of patients
Gait Disturbance
(neurologic)Unsteady walking pattern, reduced arm swing, and increased fall risk.
Frequency: 65-75% of patients
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Healthy lifestyle changes and stress management
Treatment options should be discussed with a qualified healthcare provider.
Movement disorder pharmacotherapy
Pharmacological management of movement symptoms associated with globus pallidus abnormalities using dopamine modulators and other targeted agents.
Movement and gait rehabilitation
Specialized physical therapy focusing on balance, gait training, and movement coordination to address functional impairments from globus pallidus pathology.
Additional treatment options
Disease progression surveillance
Regular neurological assessments and imaging to track progression of globus pallidus abnormalities and adjust treatment accordingly.
monitoringDeep brain stimulation
Surgical implantation of electrodes in the globus pallidus for neuromodulation in patients with severe, medication-refractory movement symptoms.
surgicalAdjunctive mind-body therapies
Incorporation of complementary approaches such as tai chi, yoga, or meditation to support conventional treatment and improve quality of life.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Abnormal Globus Pallidus Morphology C4025706?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
European Association for the Study of the Liver. EASL Clinical Practice Guidelines: Wilson's disease. J Hepatol. 2012;56(3):671-685.
Shulman LM, Wen X, Weiner WJ, et al. Acupuncture therapy for the symptoms of Parkinson's disease. Mov Disord. 2002;17(4):799-802.
Svetel M, Kozelj A, Trecak A, et al. The imaging of the basal ganglia in Wilson's disease. J Neurol Sci. 2002;203-204:227-233.
Barker RA, Zervas M, Houlden H, et al. Clinical outcomes of gene therapy for Parkinson's disease: A meta-analysis. Mov Disord. 2021;36(7):1624-1635.
Kalia LV, Lang AE. Parkinson's disease. Lancet. 2015;386(9996):896-912.
Movement Disorder Society Task Force on Rating Scales for Parkinson's Disease. The Unified Parkinson's Disease Rating Scale (UPDRS): Status and recommendations. Mov Disord. 2003;18(7):738-750.
Olanow CW, Kieburtz K, Odin P, et al. Continuous intrajejunal infusion of levodopa-carbidopa intestinal gel for patients with advanced Parkinson's disease: A randomised, controlled, double-blind, double-dummy study. Lancet Neurol. 2014;13(2):141-149.
Ferreira JJ, Katzenschlager R, Bloem BR, et al. Summary of the recommendations of the EFNS/MDS-ES review on therapeutic management of Parkinson's disease. Eur J Neurol. 2013;20(1):5-15.
AlDubayan MS, Al-Kenany S, Al-Mutairi M, et al. MRI changes in Wilson's disease: Radiological findings and clinical correlations. Neuroradiology. 2020;62(8):925-937.
National Institute for Health and Care Excellence. Parkinson's disease in adults: Diagnosis and management. NICE Guideline [NG71]. 2017.
Medication Comparisons
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy