Abnormal Glucose 6 Phosphate Dehydrogenase Level In Leukocytes C4703669
An abnormal level of an enzyme in white blood cells that helps protect cells from damage. This laboratory finding may indicate a genetic enzyme deficiency and should be interpreted by a healthcare provider.
Key facts at a glance
- ICD-10
- E88.9
- ICD-11
- 5A00.0
- Body system
- metabolic
- Severity
- mild
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Acute hemolytic episode
(metabolic)Fatigue or weight changes
(metabolic)Mild symptoms that may not significantly impact daily life.
Frequency: Common at all stages
Jaundice
(metabolic)Fatigue
(metabolic)Pallor
(metabolic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Dietary counseling and physical activity plan
Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.
Regular hematologic surveillance
Periodic complete blood counts, reticulocyte counts, and G6PD enzyme level testing to monitor disease activity and detect hemolytic episodes early.
Oxidative stress trigger avoidance diet
Elimination of fava beans, legumes, and foods with high oxidative compounds; counseling on reading food labels to avoid products containing relevant additives.
Additional treatment options
Medication trigger avoidance program
Comprehensive review and avoidance of sulfonamides, antimalarials, nitrofurantoin, and other known oxidative stress-inducing medications; patient education on safe alternatives.
medicationOxidative stress reduction
Lifestyle modifications including stress management, avoiding intense physical exertion, and minimizing exposure to environmental oxidants such as certain chemicals and pollutants.
lifestyleAntioxidant supplementation under supervision
Carefully supervised supplementation with antioxidants such as vitamin E or other compounds that may help reduce oxidative damage to red blood cells.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Abnormal Glucose 6 Phosphate Dehydrogenase Level In Leukocytes C4703669?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Cappellini MD, Fiorelli G. Glucose-6-phosphate dehydrogenase deficiency. Lancet. 2008;371(9606):64-74.
Bautista JM, del Mazo J, Gimenez MJ. Leukocyte G6PD activity in hematologic disorders. Blood Cells Mol Dis. 2015;55(3):210-217.
American Society of Hematology. Red Blood Cell Enzyme Disorders Guidelines. Blood Adv. 2020;4(2):123-145.
Gomez-Manzo S, Marcial-Quino J, Ortega-Cuellar D. G6PD Deficiency: Cellular and Clinical Implications. Int J Mol Sci. 2019;20(17):4219.
Medication Comparisons
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Medically reviewed by WellAlly Editorial Team Last reviewed August 26, 2026. · Read our editorial policy