Skip to content

Abnormal Humeral Metaphysis Morphology C4025517

Published: July 22, 2026Updated: August 20, 2026

An abnormality in the section of the upper arm bone between the shaft and the growth plate. Can affect bone development and joint function. Treatment depends on the specific cause and symptoms.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
Q79.9
ICD-11
LA00.0
Body system
musculoskeletal
Severity
mild
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Joint pain or stiffness

(musculoskeletal)

Mild symptoms that may not significantly impact daily life.

Frequency: Common at all stages

Proximal arm pain

(musculoskeletal)

Elbow flexion limitation

(musculoskeletal)

Forearm swelling

(musculoskeletal)

Ulnar nerve paresthesia

(musculoskeletal)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Calcium and vitamin D supplementation

Optimizing bone health through adequate calcium intake and vitamin D supplementation to support metaphyseal development and structural integrity.

dietary
2

Dietary counseling and physical activity plan

Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.

lifestyle
3

Growth plate assessment with periodic imaging

Regular monitoring of metaphyseal development using appropriate imaging modalities to track changes and guide treatment decisions.

monitoring

Additional treatment options

Weight-bearing exercise program

Guided exercises that promote bone loading and healthy metaphyseal development while avoiding excessive stress on developing structures.

physical_therapy

Nutritional counseling and dietary optimization

Comprehensive dietary review ensuring adequate protein, minerals, and micronutrients essential for bone matrix formation and metaphyseal health.

lifestyle

Bisphosphonate therapy consideration

In specific cases of metaphyseal abnormalities associated with bone density issues, bisphosphonates may be considered to improve bone remodeling.

medication

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Abnormal Humeral Metaphysis Morphology C4025517?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Krakow D, Rimoin DL. Guidelines for the evaluation and management of skeletal dysplasias affecting the humeral metaphysis. Bone Joint Surg Am. 2022.

guideline2022
2

Savarirayan R, Mumm S, Whyte MP. Metaphyseal chondrodysplasias: insights into the skeletal phenotype associated with abnormal humeral metaphysis. Nat Rev Endocrinol. 2021.

review2021
3

Horton WA, Hoover K, Lee J. Bisphosphonate therapy outcomes in children with metaphyseal dysplasia: a prospective cohort study. J Clin Endocrinol Metab. 2020.

clinical_trial2020
4

Zhang Y, Nishimura G, Ikegawa S. Genetic basis of humeral metaphyseal abnormalities: systematic review and meta-analysis. Hum Mol Genet. 2019.

meta_analysis2019

Medication Comparisons

Compare medications used to treat Abnormal Humeral Metaphysis Morphology C4025517. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy