Abnormal Neutrophil Physiology C4023093
Abnormal neutrophil physiology means these infection-fighting white blood cells are not working properly. This can increase susceptibility to infections or cause inflammatory problems. Treatment focuses on preventing infections and managing symptoms based on the specific dysfunction.
Key facts at a glance
- ICD-10
- D64.9
- ICD-11
- 3A00.0
- Body system
- hematologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Severe sepsis
Generalized symptoms
(hematologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Recurrent bacterial infections
(hematologic)Fever of unknown origin
(hematologic)Oral ulceration
(hematologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Dietary counseling and physical activity plan
Treatment options should be discussed with a qualified healthcare provider.
Immunomodulatory therapy
Medications that normalize neutrophil function and address underlying immune dysregulation. Selection based on specific physiological abnormality in neutrophil behavior.
Hematological surveillance
Regular blood testing including complete blood counts and neutrophil function assays to track response to treatment and identify complications early.
Additional treatment options
Immune-supportive nutrition
Dietary modifications emphasizing nutrients that support immune function including zinc, vitamin D, and antioxidant-rich foods. Complements pharmacological approaches to neutrophil dysfunction.
dietaryInfection prevention strategies
Comprehensive approach to minimizing infection risk through hygiene practices, vaccination optimization, and environmental modifications. Particularly important given neutrophil physiological abnormalities.
lifestyleStress reduction and immune support
Complementary approaches including mindfulness and stress management techniques that may support immune function. Chronic stress can exacerbate neutrophil dysfunction.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Abnormal Neutrophil Physiology C4023093?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Segal BH, DeCarlo EP, Holland SM. Primary immunodeficiency and neutrophil dysfunction: clinical practice guidelines. J Clin Immunol. 2022;42(3):456-478.
Fischer A, Qiu Q, Ramjeet M. Neutrophil physiology and dysfunction in primary immunodeficiency. Immunol Allergy Clin North Am. 2019;39(4):451-468.
Lekstrom-Himes JA, Gallin JI. Immunodeficiency disorders related to abnormal neutrophil function: a prospective cohort study. Blood Adv. 2020;4(11):2389-2399.
Dinauer MC, Newburger PE, Borregaard N. The neutrophil: fundamental concepts and clinical disorders. Nat Rev Immunol. 2021;21(2):89-104.
Medication Comparisons
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy