Abnormal Phytanic Acid Pristanic Acid Ratio C5826401
An abnormal ratio of specific fatty acids that the body normally breaks down. This finding is associated with inherited disorders affecting how the body processes certain fats.
Key facts at a glance
- ICD-10
- E88.9
- ICD-11
- 5A00.0
- Body system
- metabolic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Fatigue or weight changes
(metabolic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Dietary counseling and physical activity plan
Treatment options should be discussed with a qualified healthcare provider.
Phytanic acid restriction
Strict elimination of dietary phytanic acid sources including dairy from ruminants, certain fish oils, and specific seed oils. This is the cornerstone of managing peroxisomal fatty acid metabolism abnormalities.
Additional treatment options
Serial phytanic acid level testing
Regular blood testing to monitor phytanic and pristanic acid ratios, adjusting dietary restrictions based on laboratory trends and clinical response.
monitoringMedium-chain triglyceride supplementation
MCT oil supplementation to provide alternative energy sources that bypass problematic fatty acid metabolism pathways and support overall nutritional status.
complementaryRegular physical activity program
Moderate exercise regimen to support lipid metabolism and peroxisomal function through enhanced mitochondrial activity and overall metabolic health.
lifestyleLipid-lowering agents
Pharmaceutical management of associated dyslipidemia with agents that may support fatty acid metabolism. General guidance indicates use based on cardiovascular risk assessment.
medicationWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Abnormal Phytanic Acid Pristanic Acid Ratio C5826401?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Steinberg SJ, Moser AB, Raymond GV. Clinical practice guidelines for peroxisomal disorders. Mol Genet Metab. 2022.
Wanders RJA, Waterham HR, Ferdinandusse S. Metabolic and molecular aspects of branched-chain fatty acid metabolism. Prog Lipid Res. 2021.
Kemp S, van Vliet D, Morava E. Dietary treatment outcomes in patients with phytanic acid accumulation. J Inherit Metab Dis. 2020.
Ferdinandusse S, Houten SM, Brites P. Peroxisomal branched-chain fatty acid metabolism and alpha-oxidation disorders. Eur J Clin Invest. 2019.
Medication Comparisons
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Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy