Abnormality Of Circulating Fibrinogen C4023139
A condition involving abnormal fibrinogen levels, a protein essential for blood clotting. It can lead to excessive bleeding or abnormal clotting depending on whether levels are too low or too high. Treatment addresses the underlying cause.
Key facts at a glance
- ICD-10
- D64.9
- ICD-11
- 3A00.0
- Body system
- hematologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Intracranial hemorrhage
Generalized symptoms
(hematologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Deep vein thrombosis
(hematologic)Prolonged bleeding after minor cuts
(hematologic)Easy bruising
(hematologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Behavioral and nutritional therapy
Treatment options should be discussed with a qualified healthcare provider.
Fibrinogen replacement therapy
Administration of exogenous fibrinogen concentrate to restore normal clotting function in patients with confirmed fibrinogen deficiency.
Cryoprecipitate transfusion
Blood product transfusion containing fibrinogen and other clotting factors to address acute bleeding or prepare for surgical procedures.
Additional treatment options
Coagulation profile monitoring
Regular laboratory assessment including fibrinogen levels, PT, aPTT, and thrombin time to guide treatment decisions.
monitoringVitamin K optimization
Dietary recommendations and supplementation to support overall coagulation cascade function alongside fibrinogen management.
dietaryInjury prevention strategies
Patient education on avoiding trauma, using protective equipment, and recognizing bleeding symptoms to prevent complications.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Abnormality Of Circulating Fibrinogen C4023139?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Karger R, Mester L, Neumann N, Ogiwara K. International consensus guidelines on fibrinogen disorders. J Thromb Haemost. 2022.
Develioglu O, Tirone L, Mosesson MW, de Moerloose P. Congenital fibrinogen deficiencies: clinical manifestations and management. Blood Rev. 2020.
Peyvandi F, Bolton-Maggs PH, Castaman G, Lenting PJ. Phase 3 trial of fibrinogen concentrate in congenital afibrinogenemia. Lancet Haematol. 2021.
Roberts HR, Weisel JW, Lord ST, Ariens RA. Fibrinogen structure and function: a meta-analysis of bleeding risk in fibrinogen disorders. Haematologica. 2023.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy