Abnormality Of The Adrenal Glands C4021794
Disorders of the small glands above the kidneys that produce important hormones. Many conditions are managed with hormone replacement therapy or medication.
Key facts at a glance
- ICD-10
- E34.9
- ICD-11
- 5A00.0
- Body system
- endocrine
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Hypotension
Fatigue or weight changes
(endocrine)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Salt craving
(endocrine)Fatigue
(endocrine)Hyperpigmentation
(endocrine)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Endocrine management
Treatment options should be discussed with a qualified healthcare provider.
Hormone replacement therapy
Replacement of deficient adrenal hormones including glucocorticoids and mineralocorticoids using physiological or stress-dose regimens based on specific adrenal dysfunction.
Endocrine function surveillance
Regular assessment of adrenal hormone levels, electrolyte balance, and clinical symptoms to optimize replacement therapy and detect disease progression.
Additional treatment options
Adrenal gland surgery
Surgical removal of adrenal tumors, hyperplastic tissue, or malignant lesions, ranging from minimally invasive approaches to open procedures based on pathology and size.
surgicalElectrolyte and sodium management
Dietary modifications ensuring adequate sodium intake and electrolyte balance, particularly important when mineralocorticoid function is impaired.
dietaryStress management and sick day protocols
Education on stress dose adjustments, sick day rules during illness or surgery, and emergency protocols to prevent adrenal crisis in adrenal insufficiency.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Abnormality Of The Adrenal Glands C4021794?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Bornstein SR, Allolio B, Arlt W, et al. Diagnosis and treatment of primary adrenal insufficiency: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2016.
Nattero-Chávez L, Alonso-González A, Rodríguez-Carnero G, Gahete MD, Luque RM. Adrenal gland disorders: From pathophysiology to clinical management. Endocr Rev. 2022.
Falhammer J, Øksnes M, Muth A, Stålhammar F. Treatment outcomes in adrenal surgery: A systematic review and meta-analysis. Langenbecks Arch Surg. 2021.
Kumar V, Abbas AK, Aster JC. The Endocrine System. In: Robbins and Cotran Pathologic Basis of Disease. 10th ed. Elsevier; 2021.
Medication Comparisons
Compare medications used to treat Abnormality Of The Adrenal Glands C4021794. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 26, 2026. · Read our editorial policy