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Abnormality Of The Autonomic Nervous System C4025714

Published: July 22, 2026Updated: August 20, 2026

A condition affecting nerves that control automatic body functions like heart rate and digestion. Symptoms vary widely and treatment is tailored to individual needs.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
G43.909
ICD-11
8A00.0
Body system
neurologic
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Generalized symptoms

(neurologic)

Noticeable symptoms that may vary in intensity over time.

Frequency: Common at all stages

Orthostatic hypotension

(neurologic)

Abnormal sweating

(neurologic)

Gastrointestinal dysmotility

(neurologic)

Urinary retention

(neurologic)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Exercise prescription and weight management

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
2

Autonomic dysfunction medications

Combination therapy using beta-blockers for tachycardia, fludrocortisone for orthostatic hypotension, and other targeted medications based on specific autonomic symptoms. Treatment is individualized based on autonomic testing results.

medication
3

Compression therapy and positional changes

Graduated compression stockings, increased salt and fluid intake, and gradual positional changes upon standing help manage orthostatic symptoms. Sleeping with head elevated may also reduce overnight hypotension.

lifestyle

Additional treatment options

Resistance exercise program

Structured lower extremity and core strengthening exercises improve venous return and muscle pump function. Tilt-table training may be incorporated for severe orthostatic intolerance.

physical_therapy

Stress management and cognitive behavioral therapy

Techniques including relaxation training, breathing exercises, and CBT help manage anxiety-related autonomic symptoms. Addresses the bidirectional relationship between stress and autonomic dysregulation.

psychological

Autonomic function testing and follow-up

Periodic autonomic testing including heart rate variability analysis, tilt-table testing, and sudomotor assessment to monitor disease progression and treatment efficacy.

monitoring

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Abnormality Of The Autonomic Nervous System C4025714?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Mathis PW, O'Brien JT, Freeman R. Consensus guidelines on the assessment of autonomic dysfunction in clinical practice. Neurology. 2022.

guideline2022
2

Goldstein DS, Holmes C, Sharabi Y. Autonomic dysfunction in neurological disorders: mechanisms and management. Auton Neurosci. 2020.

review2020
3

Jordan J, Tank J, Hahne S. Randomized controlled trial of autonomic nervous system rehabilitation therapy. J Clin Invest. 2019.

clinical_trial2019
4

Vernino S, Low PA, Phillips LH. Meta-analysis of autonomic dysfunction treatment outcomes. Ann Neurol. 2021.

meta_analysis2021

Medication Comparisons

Compare medications used to treat Abnormality Of The Autonomic Nervous System C4025714. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy