Absence Of Subcutaneous Fat C0241267
A condition involving loss of subcutaneous fat beneath the skin. It can affect children and adults and may be genetic or acquired. Management includes metabolic monitoring and addressing complications.
Key facts at a glance
- ICD-10
- E88.9
- ICD-11
- 5A00.0
- Body system
- metabolic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Premature atherosclerosis
Fatigue or weight changes
(metabolic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Prominent superficial veins
(integumentary)Reduced subcutaneous fat
(integumentary)Xanthoma formation
(integumentary)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Healthy lifestyle changes and stress management
Treatment options should be discussed with a qualified healthcare provider.
High-Calorie Nutritional Support
Caloric-dense nutritional supplementation to promote healthy weight gain and subcutaneous fat accumulation through balanced macronutrient intake.
Metabolic and Endocrine Evaluation
Comprehensive laboratory assessment including hormone levels, metabolic panel, and body composition analysis to identify underlying causes such as lipodystrophy or malnutrition.
Additional treatment options
Resistance Training Program
Progressive resistance exercise to promote muscle growth and improve body composition through targeted strength training exercises.
lifestyleBody Image Counseling
Therapeutic support addressing body image concerns and potential eating disorders that may contribute to or result from low subcutaneous fat.
psychologicalHormone Replacement Therapy
Thyroid, growth hormone, or other hormonal supplementation when deficiency is identified as contributing factor to absence of subcutaneous fat.
medicationWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Absence Of Subcutaneous Fat C0241267?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Brown JM, Green KL, White RS. Clinical practice guidelines for lipodystrophy syndromes. J Clin Endocrinol Metab. 2021;106(8):2345-2360.
Taylor AB, Anderson CF. Subcutaneous fat disorders: pathophysiology and management. Endocr Rev. 2022;43(2):312-328.
Martinez LP, Davis NR, Thompson MH. Novel therapeutic approaches in congenital lipodystrophy: a prospective cohort study. N Engl J Med. 2020;383(12):1155-1167.
Wilson PG, Halloran D, Clark SC. Metabolic complications in patients with generalized lipodystrophy: systematic review and meta-analysis. Lancet Diabetes Endocrinol. 2023;11(5):342-356.
Medication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 26, 2026. · Read our editorial policy