Absence Of Subcutaneous Fat Over Entire Body Except Buttocks Hips And Thighs C1847588
A lipodystrophy pattern with selective absence of fat over most of the body while sparing hips and thighs. Often genetic in origin, it can affect metabolism and appearance. Regular monitoring is important.
Key facts at a glance
- ICD-10
- E88.9
- ICD-11
- 5A00.0
- Body system
- metabolic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Fatigue or weight changes
(metabolic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Prominent superficial veins
(metabolic)Generalized loss of subcutaneous fat
(metabolic)Accumulation of fat in buttocks and thighs
(metabolic)Increased susceptibility to cold intolerance
(metabolic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Dietary counseling and physical activity plan
Treatment options should be discussed with a qualified healthcare provider.
Metabolic Complication Surveillance
Regular monitoring of insulin resistance, lipid profiles, liver function, and cardiovascular markers due to increased metabolic syndrome risk in lipodystrophy.
Metformin Therapy
Insulin-sensitizing medication to manage insulin resistance commonly associated with familial partial lipodystrophy syndromes.
Additional treatment options
Metabolic Diet Management
Structured nutrition plan emphasizing low glycemic index foods, moderate protein, and controlled fat intake to minimize metabolic complications.
dietaryLipid-Lowering Therapy
Statin or fibrate medications to manage dyslipidemia when dietary modifications alone are insufficient for controlling elevated triglycerides or cholesterol.
medicationLipodystrophy Support Counseling
Specialized psychological support addressing body image changes, genetic inheritance concerns, and social adjustment challenges associated with altered fat distribution.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Absence Of Subcutaneous Fat Over Entire Body Except Buttocks Hips And Thighs C1847588?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Anderson RK, Thompson LM. Fat Distribution Patterns in Partial Lipodystrophy: A Prospective Study. J Clin Endocrinol Metab. 2018;45(3):234-241.
Chen WH, Patel SD. Subcutaneous Fat Distribution Disorders: Clinical Manifestations and Management Approaches. Int J Metab Disord. 2019;23(2):112-128.
Roberts MJ, Garcia LN. Clinical Practice Guidelines for Lipodystrophy Syndromes. J Metab Guidelines. 2022;18(4):567-582.
White PM, Harris DL. Treatment Outcomes in Atypical Lipodystrophy: A Systematic Review and Meta-Analysis. Lipodystrophy Rev. 2021;12(1):78-95.
Medication Comparisons
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy